Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 10/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.44 |
| ▸ | F10 | P00742 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7406978 | 0.92 | HDAC3 (0.55) | HDAC3HDAC1HDAC2CHRM3 | |
| SCHEMBL5224718 | 0.82 | HDAC3 (0.42) | HDAC3HDAC1F10 | |
| SCHEMBL5258542 | 0.82 | CHRM3 (0.50) | HDAC3HDAC1HDAC2CHRM3F10 | |
| SCHEMBL5221853 | 0.82 | MAPK1 (0.46) | CHRM3F10 | |
| Hydrochloric Acid SCHEMBL5225043 | 0.81 | HDAC3 (0.41) | HDAC3HDAC1F10 | |
| SCHEMBL5228823 | 0.79 | F10 (0.53) | HDAC3HDAC1HDAC2CHRM3F10 | |
| SCHEMBL5260230 | 0.78 | F10 (0.52) | HDAC3HDAC1HDAC2CHRM3F10 | |
| SCHEMBL5227734 | 0.78 | F10 (0.40) | HDAC3HDAC1HDAC2CHRM3F10 | |
| SCHEMBL5223035 | 0.78 | F10 (0.43) | HDAC3HDAC1HDAC2CHRM3F10 | |
| SCHEMBL5224739 | 0.78 | F10 (0.42) | HDAC3HDAC1HDAC2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1014962-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2007-06-27 | — | — | EP | disclosed |
| US-6605626-B2 | Benzamide inhibitors of factor Xa | ELI LILLY AND COMPANY | 2003-08-12 | — | — | US | disclosed |
| US-20020120007-A1 | Benzamide inhibitors of factor Xa | BEIGHT DOUGLAS WADE (US) | 2002-08-29 | — | — | US | disclosed |
| US-6313122-B1 | AS INHIBITORS OF FACTOR XA AND ARE USED AS ANTICOAGULANTS IN MAMMALS | ELI LILLY AND COMPANY | 2001-11-06 | — | — | US | disclosed |
| EP-1014962-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999000121-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020120007-A1 | Benzamide inhibitors of factor Xa | TFPI, F11, F12 | HDAC3 156/4885HDAC1 61/4885HDAC2 166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.