SCHEMBL5224718

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Hydrochloric Acid SCHEMBL5225043	0.99	HDAC3 (0.41)	HDAC3HDAC1F10HTR4ITGB3
	SCHEMBL5222501	0.82	HDAC3 (0.46)	HDAC3HDAC1F10
	SCHEMBL5223909	0.80	F10 (0.48)	HDAC3HDAC1F10
	SCHEMBL6168131	0.78	F10 (0.48)	F10ITGB3ITGA2BAOC3
	SCHEMBL7406978	0.77	HDAC3 (0.55)	HDAC3HDAC1
	SCHEMBL5222775	0.76	MEN1 (0.47)	HDAC3HDAC1F10ITGB3ITGA2B
	SCHEMBL6168128	0.76	F10 (0.46)	F10ITGB3ITGA2BAOC3
	SCHEMBL5227734	0.74	F10 (0.40)	HDAC3HDAC1F10AOC3
	SCHEMBL5223035	0.74	F10 (0.43)	HDAC3HDAC1F10AOC3BDKRB1
	SCHEMBL5224739	0.74	F10 (0.42)	HDAC3HDAC1F10BDKRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.