Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16468097 | 1.00 | TDP1 (0.32) | TDP1ALDH1A1TSHRSMN1; SMN2TP53 | |
| SCHEMBL16468098 | 1.00 | TDP1 (0.32) | TDP1ALDH1A1TSHRSMN1; SMN2TP53 | |
| SCHEMBL27768583 | 0.77 | CACNA2D1 (0.31) | TDP1TSHR | |
| SCHEMBL5107564 | 0.75 | ALDH1A1 (0.35) | TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL391721 | 0.75 | ALDH1A1 (0.35) | TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL16468296 | 0.75 | ALDH1A1 (0.35) | TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL23011836 | 0.75 | — | — | |
| SCHEMBL2838775 | 0.75 | — | — | |
| SCHEMBL105440 | 0.74 | ALDH1A1 (0.43) | TDP1ALDH1A1 | |
| SCHEMBL8059213 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778213-A2 | OLIGOMERIC COMPOUNDS | KETOCYTONYX INC. (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006020137-A2 | OLIGOMERIC COMPOUNDS | KETOCYTONYX INC. (US) | 2006-02-23 | — | — | WO | disclosed |