Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | KDM6B | O15054 | 1/20 | 0.30 |
| ▸ | KDM5C | P41229 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.30 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5107564 | 1.00 | ALDH1A1 (0.35) | ALDH1A1TDP1GAAMGAMSI | |
| SCHEMBL391721 | 1.00 | ALDH1A1 (0.35) | ALDH1A1TDP1GAAMGAMSI | |
| SCHEMBL21409519 | 0.81 | ALDH1A1 (0.35) | ALDH1A1TDP1GAAMGAMSI | |
| SCHEMBL16468098 | 0.75 | TDP1 (0.32) | ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL5222528 | 0.75 | TDP1 (0.32) | ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL16468097 | 0.75 | TDP1 (0.32) | ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL516390 | 0.75 | ALDH1A1 (0.38) | ALDH1A1TDP1GAAMGAMSI | |
| SCHEMBL8059213 | 0.74 | — | — | |
| SCHEMBL516259 | 0.74 | — | — | |
| SCHEMBL182005 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12529078-B2 | Microorganisms and methods for improving product yields on methanol using acetyl-CoA synthesis | GENOMATICA, INC. (US) | 2026-01-20 | — | — | US | disclosed |
| US-20240294950-A1 | MICROORGANISMS AND METHODS FOR IMPROVING PRODUCT YIELDS ON METHANOL USING ACETYL-COA SYNTHESIS | AGAIN BIO APS (DK) | 2024-09-05 | — | — | US | disclosed |
| EP-4296364-A2 | MICROORGANISMS AND METHODS FOR IMPROVING PRODUCT YIELDS ON METHANOL USING ACETYL-COA SYNTHESIS | Genomatica, Inc. (US) | 2023-12-27 | — | — | EP | disclosed |
| EP-3967747-B1 | MICROORGANISMS AND METHODS FOR IMPROVING PRODUCT YIELDS ON METHANOL USING ACETYL-COA SYNTHESIS | GENOMATICA INC (US) | 2023-11-08 | — | — | EP | disclosed |
| US-20220220511-A1 | MICROORGANISMS AND METHODS FOR PRODUCING BUTADIENE AND RELATED COMPOUNDS BY FORMATE ASSIMILATION | GENOMATICA INC (US) | 2022-07-14 | — | — | US | disclosed |
| EP-3967747-A1 | MICROORGANISMS AND METHODS FOR IMPROVING PRODUCT YIELDS ON METHANOL USING ACETYL-COA SYNTHESIS | Genomatica, Inc. (US) | 2022-03-16 | — | — | EP | disclosed |
| US-20210332393-A1 | MICROORGANISMS AND METHODS FOR IMPROVING PRODUCT YIELDS ON METHANOL USING ACETYL-COA SYNTHESIS | GENOMATICA INC (US) | 2021-10-28 | — | — | US | disclosed |
| EP-3077501-B1 | MICROORGANISMS AND METHODS FOR IMPROVING PRODUCT YIELDS ON METHANOL USING ACETYL-COA SYNTHESIS | GENOMATICA INC (US) | 2021-07-28 | — | — | EP | disclosed |
| US-10808262-B2 | Microorganisms and methods for improving product yields on methanol using acetyl-CoA synthesis | GENOMATICA, INC. (US) | 2020-10-20 | — | — | US | disclosed |
| US-20190017078-A1 | MICROORGANISMS AND METHODS FOR PRODUCING BUTADIENE AND RELATED COMPOUNDS BY FORMATE ASSIMILATION | GENOMATICA INC (US) | 2019-01-17 | — | — | US | disclosed |
| US-20170159075-A1 | MICROORGANISMS AND METHODS FOR IMPROVING PRODUCT YIELDS ON METHANOL USING ACETYL-COA SYNTHESIS | AGAIN BIO APS (DK) | 2017-06-08 | — | — | US | disclosed |
| US-20150050708-A1 | MICROORGANISMS AND METHODS FOR PRODUCING BUTADIENE AND RELATED COMPOUNDS BY FORMATE ASSIMILATION | GENOMATICA, INC. (US) | 2015-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12529078-B2 | Microorganisms and methods for improving product yields on methanol using acetyl-CoA synthesis | ALDOA, FDPS, DERA | ALDH1A1 385/4885TDP1 1431/4885GAA 1052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.