Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCPS | Q96C86 | 12/20 | 0.73 |
| ▸ | DHFR | P00374 | 9/20 | 0.73 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.58 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.58 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.58 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.58 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.58 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.58 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.58 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1155042 | 0.90 | DHFR (0.73) | DCPSDHFRCSNK1A1CSNK1DPRKCD | |
| SCHEMBL1155329 | 0.85 | DCPS (0.74) | DCPSDHFRCSNK1A1CSNK1DPRKCD | |
| SCHEMBL1155301 | 0.84 | DCPS (1.00) | DCPSDHFRCSNK1A1CSNK1DPRKCD | |
| SCHEMBL1154712 | 0.84 | DHFR (0.67) | DCPSDHFRCSNK1A1CSNK1DPRKCD | |
| SCHEMBL1154838 | 0.82 | DHFR (0.73) | DCPSDHFRCSNK1A1CSNK1DPRKCD | |
| SCHEMBL1154646 | 0.80 | DHFR (0.65) | DCPSDHFRCSNK1A1CSNK1DPRKCD | |
| SCHEMBL1154761 | 0.79 | DHFR (1.00) | DCPSDHFRCSNK1A1CSNK1DPRKCD | |
| SCHEMBL1154525 | 0.79 | DCPS (0.81) | DCPSDHFRCSNK1A1CSNK1DPRKCD | |
| SCHEMBL1155025 | 0.79 | DHFR (0.73) | DCPSDHFRCSNK1A1CSNK1DPRKCD | |
| SCHEMBL1154405 | 0.79 | DHFR (0.73) | DCPSDHFRCSNK1A1CSNK1DPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765810-A1 | 2,4-DIAMINOQUINAZOLINES FOR SPINAL MUSCULAR ATROPHY | Decode Chemistry, Inc. (US) | 2007-03-28 | — | — | EP | disclosed |
| WO-2005123724-A1 | 2,4-DIAMINOQUINAZOLINES FOR SPINAL MUSCULAR ATROPHY | DECODE CHEMISTRY, INC. (US) | 2005-12-29 | — | — | WO | disclosed |