Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | DNA2 | P51530 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27613664 | 0.80 | ALDH1A1 (0.58) | TSHRALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL29512644 | 0.80 | ALDH1A1 (0.49) | ALDH1A1POLBKDM4EHPGDCYP1A2 | |
| SCHEMBL6006263 | 0.80 | TSHR (0.56) | TSHRALDH1A1KDM4EHPGDPKM | |
| SCHEMBL17185095 | 0.74 | ALDH1A1 (0.51) | TSHRALDH1A1KDM4EHPGDCYP1A2 | |
| SCHEMBL16057602 | 0.72 | ALDH1A1 (0.49) | TSHRALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL16653775 | 0.72 | KDM4E (0.57) | TSHRALDH1A1KDM4ECYP1A2CYP2C9 | |
| SCHEMBL31056512 | 0.72 | APOBEC3A (0.52) | ALDH1A1POLBHPGDCYP1A2CYP3A4 | |
| SCHEMBL29805501 | 0.72 | KDM4E (0.60) | TSHRALDH1A1POLBKDM4EHPGD | |
| SCHEMBL15956314 | 0.71 | KDM4E (0.53) | ALDH1A1POLBKDM4EHPGDCYP1A2 | |
| SCHEMBL17769843 | 0.70 | TSHR (0.51) | TSHRALDH1A1POLBKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567488-B1 | HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | GLAXO GROUP LTD (GB) | 2007-02-21 | — | — | EP | disclosed |