Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 10/20 | 0.73 |
| ▸ | NPC1 | O15118 | 4/20 | 0.72 |
| ▸ | RAB9A | P51151 | 4/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.72 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.70 |
| ▸ | PPARG | P37231 | 6/20 | 0.69 |
| ▸ | PPARA | Q07869 | 5/20 | 0.69 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | F10 | P00742 | 1/20 | 0.62 |
| ▸ | PPARD | Q03181 | 1/20 | 0.62 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5226076 | 0.92 | NPC1 (0.71) | NR1H4NPC1RAB9AMEN1POLB | |
| SCHEMBL7243018 | 0.89 | NR1H4 (0.72) | NR1H4NPC1RAB9AMEN1POLB | |
| SCHEMBL5226517 | 0.88 | NPC1 (0.76) | NPC1RAB9AMEN1POLBKMT2A | |
| SCHEMBL5226864 | 0.87 | NR1H4 (0.77) | NR1H4PPARGPPARATP53PPARD | |
| SCHEMBL5224977 | 0.87 | NR1H4 (0.69) | NR1H4NPC1RAB9AMEN1POLB | |
| SCHEMBL7301192 | 0.87 | NPC1 (0.81) | NR1H4NPC1RAB9AMEN1KMT2A | |
| SCHEMBL7304276 | 0.87 | NPC1 (0.81) | NR1H4NPC1RAB9AMEN1KMT2A | |
| SCHEMBL5223950 | 0.86 | NR1H4 (0.71) | NR1H4NPC1RAB9APPARGPPARA | |
| SCHEMBL29903436 | 0.86 | NR1H4 (0.74) | NR1H4PPARGPPARAPPARD | |
| SCHEMBL5222902 | 0.85 | NR1H4 (0.67) | NR1H4MEN1POLBKMT2APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1014962-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2007-06-27 | — | — | EP | disclosed |
| US-6605626-B2 | Benzamide inhibitors of factor Xa | ELI LILLY AND COMPANY | 2003-08-12 | — | — | US | disclosed |
| US-20020120007-A1 | Benzamide inhibitors of factor Xa | BEIGHT DOUGLAS WADE (US) | 2002-08-29 | — | — | US | disclosed |
| US-6313122-B1 | AS INHIBITORS OF FACTOR XA AND ARE USED AS ANTICOAGULANTS IN MAMMALS | ELI LILLY AND COMPANY | 2001-11-06 | — | — | US | disclosed |
| EP-1014962-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999000121-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020120007-A1 | Benzamide inhibitors of factor Xa | TFPI, F11, F12 | NR1H4 2304/4885NPC1 1618/4885RAB9A 2658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.