SCHEMBL5223836

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14329237	0.87	GABRG2 (0.43)	GABRG2GABRB3GABRA5GABRA1GABRA3
	SCHEMBL7860222	0.83	PTPN2 (0.50)	GABRG2GABRB3GABRA5GABRA1GABRA3
	SCHEMBL29149086	0.81	NPC1 (0.39)	NPC1RAB9AMEN1HTTKMT2A
	SCHEMBL31757283	0.81	GABRG2 (0.47)	GABRG2GABRB3GABRA5GABRA1GABRA3
	SCHEMBL5619767	0.81	GABRG2 (0.47)	GABRG2GABRB3GABRA5GABRA1GABRA3
	SCHEMBL17495245	0.81	CA12 (0.46)	GABRG2GABRB3GABRA1GABRA3GABRA2
	SCHEMBL9600264	0.81	EGFR (0.50)	GABRG2GABRB3GABRA5GABRA1GABRA3
	SCHEMBL204305	0.81	SOS1 (0.45)	MEN1KMT2ACA12CA1CA2
	SCHEMBL6351877	0.80	GABRG2 (0.43)	GABRG2GABRB3GABRA5GABRA1GABRA3
	SCHEMBL27684346	0.80	GABRG2 (0.43)	GABRG2GABRB3GABRA5GABRA1GABRA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.