SCHEMBL6351877

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1185611	0.83	KMT2A (0.52)	ALDH1A1HSD17B10KDM4EMAPTALOX15
	SCHEMBL5619767	0.81	GABRG2 (0.47)	GABRG2GABRB3GABRA5GABRA1GABRA3
	SCHEMBL31757283	0.81	GABRG2 (0.47)	GABRG2GABRB3GABRA5GABRA1GABRA3
	SCHEMBL2403279	0.81	MAPT (0.47)	ALDH1A1HSD17B10KDM4EMAPTALOX15
	SCHEMBL7472823	0.81	ALOX15 (0.48)	GABRG2GABRB3GABRA1GABRA3GABRA2
	SCHEMBL9600264	0.81	EGFR (0.50)	GABRG2GABRB3GABRA5GABRA1GABRA3
	SCHEMBL140846	0.81	GAA (0.62)	ALDH1A1HSD17B10KDM4EMAPTALOX15
	SCHEMBL6817695	0.80	KDM4E (0.56)	ALDH1A1HSD17B10KDM4EMAPTALOX15
	SCHEMBL415970	0.80	ABL1 (0.50)	GABRG2GABRB3GABRA5GABRA1GABRA3
	SCHEMBL29517137	0.80	KDM4E (0.56)	ALDH1A1HSD17B10KDM4EMAPTALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.