SCHEMBL5224569

SCHEMBL5224569

CC1(N)C=CC([N+](=O)[O-])=CC1N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29103356 0.79
SCHEMBL29114582 0.75
SCHEMBL29129960 0.69 MAOA (0.33)
SCHEMBL16207594 0.68
SCHEMBL9707588 0.68
SCHEMBL31338542 0.68
SCHEMBL28984166 0.68 TSHR (0.31)
SCHEMBL10655901 0.67 ADORA3 (0.32)
SCHEMBL16042901 0.67
SCHEMBL8065648 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118546363-A Polyimide film and production process thereof 江苏韵升绝缘科技有限公司 2024-08-27 CN disclosed
CN-118359609-A Heterocyclic compounds, their preparation and use 益方生物科技(上海)股份有限公司 2024-07-19 CN disclosed
CN-118159533-A Heterocyclic compounds and their use 艾森医药有限公司 2024-06-07 CN disclosed
WO-2024083208-A1 KIF18A PROTEIN INHIBITOR 杭州邦顺制药有限公司 2024-04-25 WO disclosed
CN-117917405-A KIF18A protein inhibitors 杭州邦顺制药有限公司 2024-04-23 CN disclosed
CN-116997550-A N- (benzoyl) -phenylalanine compounds, pharmaceutical compositions containing same and application thereof 杭州普洛药物研究院有限公司 2023-11-03 CN disclosed
WO-2022135502-A1 MULTI-SUBSTITUTED URACIL DERIVATIVE AND USE THEREOF 广东东阳光药业有限公司 2022-06-30 WO disclosed
EP-3972967-A1 HETEROCYCLIC COMPOUNDS, PREPARATION METHODS AND USES THEREOF InventisBio Co., Ltd. (CN) 2022-03-30 EP disclosed
EP-1487824-B1 DIAMINO-PYRIMIDINES AND THEIR USE AS ANGIOGENESIS INHIBITORS SMITHKLINE BEECHAM CORP (US) 2007-06-20 EP disclosed