Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.48 |
| ▸ | PPARG | P37231 | 10/20 | 0.42 |
| ▸ | PPARD | Q03181 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5228532 | 0.94 | PPARG (0.50) | PPARAPPARGPPARDTP53MAPT | |
| SCHEMBL5264572 | 0.93 | PPARA (0.42) | PPARAPPARGPPARDKDM4ELMNA | |
| SCHEMBL5263579 | 0.88 | TP53 (0.53) | PPARAPPARGFFAR1TP53MAPT | |
| SCHEMBL5223894 | 0.87 | PPARA (0.50) | PPARAPPARGPPARDFFAR1KDM4E | |
| SCHEMBL5227814 | 0.87 | PPARA (0.46) | PPARAPPARGPPARDKDM4E | |
| SCHEMBL5228228 | 0.86 | TP53 (0.47) | PPARAPPARGPPARDFFAR1TP53 | |
| SCHEMBL5229603 | 0.85 | PPARA (0.50) | PPARAPPARGPPARDFFAR1TP53 | |
| SCHEMBL5263779 | 0.85 | FFAR1 (0.51) | PPARAPPARGFFAR1TP53MAPT | |
| SCHEMBL5226542 | 0.83 | PPARA (0.49) | PPARAPPARGPPARDFFAR1KDM4E | |
| SCHEMBL5226643 | 0.83 | KDR (0.52) | PPARAPPARGTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778654-A1 | SULFAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR UPREGULATION OF LIPID METABOLISM COMPRISING SAME | Crystalgenomics, Inc. (KR) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006006832-A1 | SULFAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR UPREGULATION OF LIPID METABOLISM COMPRISING SAME | CRYSTALGENOMICS, INC. (KR) | 2006-01-19 | — | — | WO | disclosed |