Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 4/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5227582 | 0.80 | AKT1 (0.46) | KMT2AMEN1LMNA | |
| SCHEMBL5225301 | 0.80 | RAB9A (0.54) | ALDH1A1GAAKMT2AMEN1HDAC1 | |
| Hydrochloric Acid SCHEMBL5228421 | 0.79 | MEN1 (0.45) | TSHRALDH1A1KMT2AMEN1HTT | |
| SCHEMBL7244377 | 0.72 | SLC6A4 (0.44) | ALDH1A1GAAKMT2AMEN1LMNA | |
| SCHEMBL6358261 | 0.69 | ALDH1A1 (0.66) | GPR132NR1H4TSHRALDH1A1GAA | |
| SCHEMBL28058986 | 0.68 | NR1H4 (0.71) | GPR132NR1H4TSHRALDH1A1KMT2A | |
| SCHEMBL7713160 | 0.67 | SMPD1 (0.64) | GPR132NR1H4TSHRALDH1A1GAA | |
| SCHEMBL7710629 | 0.67 | KDM4E (0.66) | NR1H4TSHRALDH1A1GAAKMT2A | |
| SCHEMBL6353185 | 0.66 | AKR1C2 (0.72) | GPR132NR1H4TSHRALDH1A1KMT2A | |
| SCHEMBL8792578 | 0.66 | NR4A2 (0.67) | GPR132NR1H4ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1014962-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2007-06-27 | — | — | EP | disclosed |
| EP-1014962-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999000121-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | disclosed |