Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15348824 | 0.85 | TSHR (0.50) | TSHRKMT2AALDH1A1TRPM8NPC1 | |
| SCHEMBL17675195 | 0.81 | TSHR (0.59) | TSHRTHRBKMT2ATP53ALDH1A1 | |
| SCHEMBL10840731 | 0.80 | TSHR (0.58) | TSHRTHRBKMT2ATP53ALDH1A1 | |
| SCHEMBL6316045 | 0.80 | TSHR (0.58) | TSHRTHRBKMT2ATP53ALDH1A1 | |
| SCHEMBL8299401 | 0.79 | ALDH1A1 (0.47) | TSHRKMT2ATP53ALDH1A1TRPM8 | |
| SCHEMBL3831838 | 0.79 | TSHR (0.56) | TSHRTHRBKMT2ATP53ALDH1A1 | |
| SCHEMBL10618369 | 0.77 | TSHR (0.55) | TSHRTHRBKMT2ATP53ALDH1A1 | |
| SCHEMBL23668046 | 0.76 | MAPT (0.54) | THRBKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL15904408 | 0.76 | TSHR (0.54) | TSHRTHRBKMT2ATP53ALDH1A1 | |
| SCHEMBL2726847 | 0.76 | TSHR (0.70) | TSHRTHRBKMT2ATP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1014962-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2007-06-27 | — | — | EP | disclosed |
| EP-1014962-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999000121-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | disclosed |