Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18765295 | 0.90 | KDM4E (0.63) | TSHRKMT2AKDM4ETHRBTP53 | |
| SCHEMBL3939111 | 0.87 | TSHR (0.46) | TSHRKMT2AKDM4ETHRBTP53 | |
| SCHEMBL7367970 | 0.87 | TSHR (0.46) | TSHRKMT2AKDM4ETHRBTP53 | |
| SCHEMBL7808323 | 0.87 | TSHR (0.46) | TSHRKMT2AKDM4ETHRBTP53 | |
| SCHEMBL5838645 | 0.85 | HSD17B10 (0.60) | TSHRKDM4ETP53RAB9AHSD17B10 | |
| SCHEMBL14507079 | 0.83 | KMT2A (0.58) | TSHRKMT2AKDM4ETP53RAB9A | |
| SCHEMBL243741 | 0.83 | POLB (0.51) | TSHRKMT2AKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL7953771 | 0.83 | TSHR (0.43) | TSHRKMT2AKDM4ETHRBTP53 | |
| SCHEMBL7749655 | 0.83 | ALDH1A1 (0.47) | TSHRKMT2AKDM4ETHRBTP53 | |
| SCHEMBL6643330 | 0.83 | FFAR1 (0.49) | TSHRKMT2AKDM4EHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6887646-B1 | Chemical amplification resist composition | MITSUBISHI RAYON CO., LTD. (JP) | 2005-05-03 | — | — | US | disclosed |
| US-20040097562-A1 | Method for treating tension-type headache | HEAD EXPLORER APS (DK) | 2004-05-20 | — | — | US | disclosed |
| US-20040097562-A1 | Method for treating tension-type headache | HEAD EXPLORER APS (DK) | 2004-05-20 | — | — | US | disclosed |
| EP-1209525-A1 | CHEMICAL AMPLIFICATION RESIST COMPOSITION | Mitsubishi Rayon Co., Ltd. (JP) | 2002-05-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097562-A1 | Method for treating tension-type headache | GRIN3A, GRIN2A, GRIK4 | TSHR 1186/4885KMT2A 40/4885KDM4E 479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.