Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 9/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | CTSD | P07339 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5222715 | 0.85 | CTSD (0.58) | CTSD | |
| SCHEMBL5217674 | 0.85 | CSNK1E (0.49) | CASRADRB2F2 | |
| SCHEMBL5383193 | 0.83 | CASR (0.46) | CASRADRB2ADRB1F2 | |
| SCHEMBL3353932 | 0.82 | BCHE (0.52) | TAAR1ADRB2ADRB1F2CTSD | |
| Hydrochloric Acid SCHEMBL5222886 | 0.82 | CASR (0.45) | CASRADRB2ADRB1F2 | |
| SCHEMBL165644 | 0.82 | BCHE (0.61) | CTSD | |
| SCHEMBL4214871 | 0.82 | BCHE (0.61) | CTSD | |
| Hydrochloric Acid SCHEMBL5225498 | 0.81 | BCHE (0.51) | TAAR1ADRB2ADRB1F2CTSD | |
| Hydrochloric Acid SCHEMBL5348922 | 0.81 | BCHE (0.60) | CTSD | |
| Hydrochloric Acid SCHEMBL6110582 | 0.81 | BCHE (0.60) | CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567488-B1 | HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | GLAXO GROUP LTD (GB) | 2007-02-21 | — | — | EP | disclosed |