Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23532657 | 0.90 | CTSD (0.50) | CTSD | |
| Hydrochloric Acid SCHEMBL23532658 | 0.90 | CTSD (0.50) | CTSD | |
| SCHEMBL5224458 | 0.85 | BACE1 (0.56) | CTSD | |
| SCHEMBL5225340 | 0.85 | CASR (0.52) | CTSD | |
| SCHEMBL5223874 | 0.84 | HTR2A (0.47) | CTSD | |
| SCHEMBL18767257 | 0.81 | CTSD (0.68) | CTSD | |
| SCHEMBL5383209 | 0.81 | CTSD (0.56) | CTSD | |
| SCHEMBL5383205 | 0.80 | CTSD (0.83) | CTSD | |
| SCHEMBL5928484 | 0.79 | CTSD (0.53) | CTSD | |
| SCHEMBL165644 | 0.79 | BCHE (0.61) | CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017066742-A1 | BACE-2 INHIBITORY COMPOUNDS AND RELATED METHODS OF USE | JORTAN PHARMACEUTICALS INC. (US) | 2017-04-20 | — | — | WO | disclosed |
| EP-1567488-B1 | HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | GLAXO GROUP LTD (GB) | 2007-02-21 | — | — | EP | disclosed |