Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 18/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 17/20 | 0.49 |
| ▸ | NQO2 | P16083 | 14/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5225817 | 0.92 | MTNR1A (0.55) | MTNR1AMTNR1BNQO2HTR1A | |
| SCHEMBL7198660 | 0.85 | MTNR1A (0.66) | MTNR1AMTNR1BNQO2HTR1A | |
| SCHEMBL6077302 | 0.85 | NQO2 (0.47) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL5223865 | 0.85 | MTNR1A (0.63) | MTNR1AMTNR1BNQO2HTR1A | |
| SCHEMBL5227718 | 0.83 | HTR1A (0.59) | MTNR1AMTNR1BNQO2HTR1A | |
| SCHEMBL6077298 | 0.79 | MTNR1A (0.47) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7198659 | 0.77 | MTNR1A (0.69) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL5223857 | 0.76 | MTNR1A (0.72) | MTNR1AMTNR1BNQO2HTR1A | |
| SCHEMBL5175120 | 0.76 | HTR1A (0.54) | MTNR1AMTNR1BNQO2HTR1A | |
| SCHEMBL5226604 | 0.76 | MTNR1A (0.61) | MTNR1AMTNR1BNQO2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998471-B1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS, METHOD FOR PREPARING AND COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2007-03-14 | — | — | EP | disclosed |
| US-6602903-B2 | Substituted O- and/or S heterocyclic compounds; powerful ligands for melatoninergic receptors. | LES LABORATORIES SERVIER (FR) | 2003-08-05 | — | — | US | disclosed |