Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 2/20 | 0.32 |
| ▸ | CDK8 | P49336 | 2/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5228810 | 0.77 | DRD1 (0.32) | DRD1 | |
| SCHEMBL5224774 | 0.68 | MAPK8 (0.33) | — | |
| SCHEMBL5224162 | 0.66 | KMT2A (0.38) | — | |
| SCHEMBL3972807 | 0.65 | CTNNB1 (0.54) | — | |
| SCHEMBL30515474 | 0.62 | KDM4E (0.33) | — | |
| SCHEMBL353705 | 0.61 | — | — | |
| SCHEMBL5216616 | 0.60 | KMT2A (0.36) | — | |
| SCHEMBL1646551 | 0.59 | — | — | |
| SCHEMBL16097786 | 0.58 | — | — | |
| SCHEMBL6427466 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1824862-A1 | SILICON COMPOUNDS AND THEIR USE | Takeda Cambridge Limited (GB) | 2007-08-29 | — | — | EP | claimed |
| WO-2006064263-A1 | SILICON COMPOUNDS AND THEIR USE | TAKEDA CAMBRIDGE LIMITED (GB) | 2006-06-22 | — | — | WO | claimed |