Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 10/20 | 0.35 |
| ▸ | FLT1 | P17948 | 8/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.34 |
| ▸ | SELE | P16581 | 3/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.33 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5224162 | 0.87 | KMT2A (0.38) | KMT2AMEN1NPC1MAPTRAB9A | |
| SCHEMBL3972807 | 0.75 | CTNNB1 (0.54) | KMT2AMEN1NPC1MAPTRAB9A | |
| SCHEMBL78647 | 0.74 | KMT2A (0.58) | KMT2AMEN1MAPTPARP1 | |
| SCHEMBL5224774 | 0.67 | MAPK8 (0.33) | KDR | |
| SCHEMBL6632075 | 0.61 | PARP1 (0.50) | NPC1MAPTRAB9APARP1 | |
| SCHEMBL79324 | 0.61 | ALDH1A1 (0.44) | SMN1; SMN2 | |
| SCHEMBL8723541 | 0.61 | ALDH1A1 (0.41) | KMT2AMEN1NPC1MAPTRAB9A | |
| SCHEMBL5228810 | 0.60 | DRD1 (0.32) | — | |
| SCHEMBL5225862 | 0.60 | CCNC (0.32) | — | |
| SCHEMBL78769 | 0.59 | KMT2A (0.66) | KMT2AMEN1MAPTPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1824863-A1 | SILICON COMPOUNDS AND THEIR USE | Takeda Cambridge Limited (GB) | 2007-08-29 | — | — | EP | disclosed |
| WO-2006064277-A1 | SILICON COMPOUNDS AND THEIR USE | TAKEDA CAMBRIDGE LIMITED (GB) | 2006-06-22 | — | — | WO | disclosed |