Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.73 |
| ▸ | NPC1 | O15118 | 6/20 | 0.65 |
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | PPARD | Q03181 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.56 |
| ▸ | F10 | P00742 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5227999 | 0.85 | NPC1 (0.69) | ABCG2NPC1RAB9APOLBMEN1 | |
| SCHEMBL5223096 | 0.84 | RAB9A (0.71) | ABCG2NPC1RAB9APOLBMEN1 | |
| SCHEMBL5226517 | 0.83 | NPC1 (0.76) | ABCG2NPC1RAB9APOLBMEN1 | |
| SCHEMBL5223218 | 0.81 | NR1H4 (0.73) | ABCG2NPC1RAB9APOLBMEN1 | |
| SCHEMBL20715740 | 0.80 | NPC1 (0.71) | ABCG2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL5225155 | 0.80 | NPC1 (0.71) | ABCG2NPC1RAB9APOLBMEN1 | |
| SCHEMBL5226076 | 0.80 | NPC1 (0.71) | ABCG2NPC1RAB9APOLBMEN1 | |
| SCHEMBL5188942 | 0.79 | NPC1 (1.00) | ABCG2NPC1RAB9APOLBMEN1 | |
| SCHEMBL1689196 | 0.77 | HDAC1 (0.78) | ABCG2F10HDAC1 | |
| SCHEMBL14855681 | 0.77 | F10 (0.72) | ABCG2NPC1RAB9APOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1014962-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2007-06-27 | — | — | EP | disclosed |
| EP-1014962-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999000121-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | disclosed |