Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16017279 | 0.86 | ALDH1A1 (0.50) | LMNACYP1A2CYP2D6CYP2C19CHRM2 | |
| SCHEMBL8349305 | 0.78 | CHRM2 (0.49) | LMNACYP1A2CYP2D6CYP2C19CHRM2 | |
| Hydrochloric Acid SCHEMBL11620409 | 0.78 | LMNA (0.50) | LMNACYP1A2CYP2D6CYP2C19CHRM2 | |
| SCHEMBL7605778 | 0.77 | CHRM2 (0.83) | CYP2D6CHRM2 | |
| Hydrochloric Acid SCHEMBL5713119 | 0.76 | CHRM2 (0.80) | LMNACHRM2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7543557 | 0.76 | CHRM2 (0.50) | LMNACYP1A2CYP2D6CYP2C19CHRM2 | |
| Hydrochloric Acid SCHEMBL3665646 | 0.76 | CHRM2 (0.80) | LMNACHRM2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7101030 | 0.76 | CHRM2 (0.50) | LMNACYP1A2CYP2D6CYP2C19CHRM2 | |
| SCHEMBL15005744 | 0.76 | CHRM2 (0.50) | LMNACYP1A2CYP2D6CYP2C19CHRM2 | |
| Hydrochloric Acid SCHEMBL5713128 | 0.76 | CHRM2 (0.80) | LMNACHRM2SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1394158-B1 | Thiophene derivatives and optical elements using the same | FUJIFILM CORP (JP) | 2007-03-21 | — | — | EP | disclosed |
| EP-1394158-A1 | Novel compounds and optical elements using the same | FUJI PHOTO FILM CO., LTD. (JP) | 2004-03-03 | — | — | EP | disclosed |