Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.51 |
| ▸ | CDK2 | P24941 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SNCA | P37840 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5226055 | 0.87 | KMT2A (0.47) | F10KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL7249077 | 0.78 | F10 (0.45) | F10GAACCNE1CDK2ALDH1A1 | |
| SCHEMBL5222235 | 0.77 | F10 (0.68) | F10KMT2AMEN1POLBRAB9A | |
| SCHEMBL22495406 | 0.75 | RAB9A (0.77) | F10KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL7256979 | 0.75 | F10 (0.73) | F10KMT2ARAB9ANPC1GAA | |
| SCHEMBL5227933 | 0.75 | F10 (0.75) | F10KMT2AMEN1POLBRAB9A | |
| SCHEMBL5224549 | 0.74 | KMT2A (0.51) | KMT2AMEN1NPC1GAAALDH1A1 | |
| SCHEMBL5410384 | 0.74 | F10 (0.81) | F10 | |
| SCHEMBL6211789 | 0.73 | POLB (0.61) | F10KMT2AMEN1POLBRAB9A | |
| SCHEMBL7371754 | 0.72 | F10 (0.55) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1014962-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2007-06-27 | — | — | EP | disclosed |
| EP-1014962-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999000121-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | disclosed |