SCHEMBL522666

SCHEMBL522666

Fc1ccc(OBOc2ccc(F)c(Cl)c2)cc1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SOS1 Q07889 3/20 0.46
HTR2A P28223 3/20 0.41
SLC6A4 P31645 3/20 0.41
KCNH2 Q12809 3/20 0.41
EGFR P00533 1/20 0.41
MAPT P10636 4/20 0.39
NPC1 O15118 2/20 0.39
HTT P42858 2/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MAPK1 P28482 1/20 0.39
HSD17B10 Q99714 1/20 0.39
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
ALDH1A1 P00352 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
KDR P35968 1/20 0.37
APP P05067 1/20 0.36
SLC2A1 P11166 1/20 0.34
RPA1 P27694 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14664865 0.83 SOS1 (0.44) SOS1HTR2ASLC6A4KCNH2EGFR
SCHEMBL522748 0.83 PPARG (0.41) HTR2ASLC6A4KCNH2MAPTKMT2A
SCHEMBL4345160 0.79 SOS1 (0.65) SOS1HTR2ASLC6A4KCNH2EGFR
SCHEMBL177743 0.79 SOS1 (0.41) SOS1HTR2ASLC6A4
SCHEMBL177501 0.79 HSP90AA1 (0.47) HTR2ASLC6A4KCNH2SMN1; SMN2HSD17B10
SCHEMBL3759344 0.76 SOS1 (0.47) SOS1HTR2ASLC6A4KCNH2EGFR
SCHEMBL1042563 0.76 MAPT (0.56) SOS1HTR2ASLC6A4KCNH2EGFR
SCHEMBL1529024 0.74 NR4A1 (0.38) SOS1MAPTSMN1; SMN2HSD17B10MEN1
SCHEMBL177568 0.74 HTR2A (0.40) HTR2ASLC6A4KCNH2RAB9AKMT2A
SCHEMBL529160 0.74 HSD17B10 (0.48) MAPTSMN1; SMN2MAPK1HSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 349 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8921299-B2 Detergents having acceptable color THE PROCTER & GAMBLE COMPANY (US) 2014-12-30 US claimed
WO-1995005081-A1 BIOCIDAL COMPOSITIONS CONTAINING ORGANOBORON COMPOUNDS U.S. BORAX INC. (US) 1995-02-23 WO claimed
US-12522813-B2 Mannanase for formulations having pH 5-12 BASF SE (DE) 2026-01-13 US disclosed
US-20250333383-A1 N-OXIDE COMPOUNDS AND USE THEREOF SK BIOPHARMACEUTICALS CO., LTD. (KR) 2025-10-30 US disclosed
US-20250282735-A1 BICYCLE COMPOUNDS AS TEAD INHIBITOR DONG-A ST CO., LTD. (KR) 2025-09-11 US disclosed
CN-120077035-A As CX32,4, 6-Trisubstituted 1,3, 5-triazines as modulators of CR1 阿斯利康(瑞典)有限公司 2025-05-30 CN disclosed
CN-114929676-B Heterocyclic carboxylate compounds as glycolate oxidase inhibitors 紫丁香疗法有限公司 2025-04-29 CN disclosed
EP-4514777-A1 N-OXIDE COMPOUNDS AND USE THEREOF SK Biopharmaceuticals Co., Ltd. (KR) 2025-03-05 EP disclosed
EP-4482824-A1 CARBOXAMIDE COMPOUNDS AS PGE2 RECEPTOR ANTAGONISTS Guangdong Newopp Biopharmaceuticals Co., Ltd. (CN) 2025-01-01 EP disclosed
CN-118976029-A Pharmaceutical composition for preventing or treating parkinson's disease or nonalcoholic steatohepatitis 韩国化学研究院 2024-11-19 CN disclosed
CN-118975434-A Organic light emitting device 株式会社LG化学 2024-11-15 CN disclosed
US-5530005-A THERAPY FOR SKIN DISORDERS, AIDS, IMMUNOSUPPRESION DISEASES SYNTEX (U.S.A.) INC. (US) 1996-06-25 US disclosed
US-5527827-A ANTIASTHMATIC, ANTIALLERGIC, ANTIINFLAMMATORY AND CYTOPROTECTIVE AGENTS MERCK FROSST CANADA, INC. (CA) 1996-06-18 US disclosed
WO-1996013491-A1 BISARYLCARBINOL CINNAMIC ACIDS AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS MERCK FROSST CANADA INC. (CA) 1996-05-09 WO disclosed
WO-1996013500-A1 BISARYLCARBINOL DERIVATIVES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS MERCK FROSST CANADA INC. (CA) 1996-05-09 WO disclosed
EP-0691966-A1 QUINOLINES AS TYPE IV PHOSPHODIESTERASE INHIBITORS SYNTEX (U.S.A.) INC. (US) 1996-01-17 EP disclosed
US-5475003-A Antiinflammatory agent, immunosuppressive, antiallergens, bronchodilators, analgens SYNTEX (U.S.A.) INC. (US) 1995-12-12 US disclosed
US-5455252-A Antiinflammatory agent, immunosuppressant, antiallergen, skin disorders, bronchodilator, analgesic SYNTEX (U.S.A.) INC. (US) 1995-10-03 US disclosed
WO-1995005081-A1 BIOCIDAL COMPOSITIONS CONTAINING ORGANOBORON COMPOUNDS U.S. BORAX INC. (US) 1995-02-23 WO disclosed
WO-1994022852-A1 QUINOLINES AS TYPE IV PHOSPHODIESTERASE INHIBITORS SYNTEX (U.S.A.) INC. (US) 1994-10-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250333383-A1 N-OXIDE COMPOUNDS AND USE THEREOF SCNN1B, SCN1B, SCN2B SOS1 1346/4885HTR2A 1313/4885SLC6A4 146/4885
US-20250282735-A1 BICYCLE COMPOUNDS AS TEAD INHIBITOR TEAD1, TEAD2, TEAD3 SOS1 1568/4885HTR2A 4165/4885SLC6A4 1253/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.