Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5851002 | 0.83 | KDM4E (0.59) | KDM4EHSD17B10MAPK1EGFRLMNA | |
| SCHEMBL28181864 | 0.77 | CHRNB2 (0.43) | KDM4EHSD17B10MAPK1EGFRLMNA | |
| SCHEMBL1101269 | 0.76 | ALDH1A1 (0.42) | KDM4EHSD17B10MAPK1EGFRLMNA | |
| SCHEMBL2188020 | 0.72 | MAPT (0.72) | KDM4ELMNAALDH1A1HPGDMEN1 | |
| SCHEMBL8097842 | 0.72 | KDM4E (0.48) | KDM4EEGFRLMNAALDH1A1MEN1 | |
| SCHEMBL7114553 | 0.72 | KDM4E (0.48) | KDM4EEGFRLMNAALDH1A1MEN1 | |
| SCHEMBL7114556 | 0.72 | KDM4E (0.48) | KDM4EEGFRLMNAALDH1A1MEN1 | |
| SCHEMBL19193162 | 0.71 | KDM4E (0.60) | KDM4EHSD17B10EGFRLMNAALDH1A1 | |
| SCHEMBL20037094 | 0.71 | KDM4E (0.61) | KDM4EHSD17B10EGFRLMNAALDH1A1 | |
| SCHEMBL10478444 | 0.71 | KDM4E (0.53) | KDM4EHSD17B10MAPK1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412336-A4 | PEPTOID COMPOUNDS | UNIV WOLLONGONG (AU) | 2007-08-29 | — | — | EP | disclosed |
| EP-1412336-A1 | PEPTOID COMPOUNDS | UNIVERSITY OF WOLLONGONG (AU) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003002545-A1 | PEPTOID COMPOUNDS | UNIVERSITY OF WOLLONGONG (AU) | 2003-01-09 | — | — | WO | disclosed |