Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | SLC6A1 | P30531 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28152186 | 1.00 | KCNK3 (0.52) | KCNK3LMNASMN1; SMN2SLC6A1CYP3A4 | |
| SCHEMBL669604 | 0.98 | KCNK3 (0.54) | KCNK3LMNASMN1; SMN2SLC6A1CYP3A4 | |
| SCHEMBL23551811 | 0.98 | KCNK3 (0.54) | KCNK3LMNASMN1; SMN2SLC6A1CYP3A4 | |
| SCHEMBL28148146 | 0.98 | KCNK3 (0.54) | KCNK3LMNASMN1; SMN2SLC6A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL28151982 | 0.96 | KCNK3 (0.52) | KCNK3LMNASMN1; SMN2SLC6A1CYP3A4 | |
| SCHEMBL3145758 | 0.93 | LMNA (0.48) | KCNK3LMNASMN1; SMN2SLC6A1NR1I2 | |
| SCHEMBL1887364 | 0.93 | LMNA (0.48) | KCNK3LMNASMN1; SMN2SLC6A1NR1I2 | |
| SCHEMBL1887361 | 0.93 | LMNA (0.48) | KCNK3LMNASMN1; SMN2SLC6A1NR1I2 | |
| Hydrochloric Acid SCHEMBL9155039 | 0.91 | LMNA (0.47) | KCNK3LMNASMN1; SMN2SLC6A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL9155025 | 0.91 | LMNA (0.47) | KCNK3LMNASMN1; SMN2SLC6A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814893-A2 | NOVEL LINCOMYCIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | Vicuron Pharmaceuticals, Inc. (US) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006055070-A2 | NOVEL LINCOMYCIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2006-05-26 | — | — | WO | disclosed |