Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 6/20 | 0.42 |
| ▸ | REN | P00797 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PEPD | P12955 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3145758 | 1.00 | LMNA (0.48) | LMNAKCNK3NR1I2SMN1; SMN2ACE | |
| SCHEMBL1887364 | 1.00 | LMNA (0.48) | LMNAKCNK3NR1I2SMN1; SMN2ACE | |
| Hydrochloric Acid SCHEMBL9155025 | 0.98 | LMNA (0.47) | LMNAKCNK3NR1I2SMN1; SMN2ACE | |
| Hydrochloric Acid SCHEMBL9155039 | 0.98 | LMNA (0.47) | LMNAKCNK3NR1I2SMN1; SMN2ACE | |
| SCHEMBL23551811 | 0.94 | KCNK3 (0.54) | LMNAKCNK3NR1I2SMN1; SMN2ACE | |
| SCHEMBL28148146 | 0.94 | KCNK3 (0.54) | LMNAKCNK3NR1I2SMN1; SMN2ACE | |
| SCHEMBL669604 | 0.94 | KCNK3 (0.54) | LMNAKCNK3NR1I2SMN1; SMN2ACE | |
| SCHEMBL28152186 | 0.93 | KCNK3 (0.52) | LMNAKCNK3NR1I2SMN1; SMN2SLC6A1 | |
| SCHEMBL5226944 | 0.93 | KCNK3 (0.52) | LMNAKCNK3NR1I2SMN1; SMN2SLC6A1 | |
| Hydrochloric Acid SCHEMBL28151982 | 0.93 | KCNK3 (0.52) | LMNAKCNK3NR1I2SMN1; SMN2SLC6A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105566411-B | Lincomycin biosynthesis intermediate product and preparation method and application thereof | 中国科学院上海有机化学研究所 | 2020-11-13 | — | — | CN | claimed |
| US-20180251486-A1 | LINCOMYCIN BIOSYNTHETIC INTERMEDIATES, METHOD FOR PREPARATION, AND USE THEREOF | HUZHOU CENTER OF BIO-SYNTHETIC INNOVATION, SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2018-09-06 | — | — | US | claimed |
| EP-3154568-A1 | NON-CANONICAL INSULINS AND THEIR USES | California Institute of Technology (US) | 2017-04-19 | — | — | EP | claimed |
| CN-105566411-A | Lincomycin biosynthesized intermediate product and preparation method and use thereof | SHANGHAI INST ORGANIC CHEMISTRY CAS | 2016-05-11 | — | — | CN | claimed |
| WO-2015191705-A1 | NON-CANONICAL INSULINS AND THEIR USES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2015-12-17 | — | — | WO | claimed |
| US-20150353619-A1 | Non-Canonical Insulins and Their Uses | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2015-12-10 | — | — | US | claimed |
| US-5665371-A | SIDE EFFECT REDUCTION | HOERRMANN WILHELM (DE) | 1997-09-09 | — | — | US | claimed |
| EP-0253785-B1 | EFFICIENT STEREOCONSERVATIVE SYNTHESES OF 1-SUBSTITUTED (S)- AND (R)-2-AMINOMETHYLPYRROLIDINES AND INTERMEDIATES THEREIN | ASTRA LAKEMEDEL AKTIEBOLAG (SE) | 1992-11-11 | — | — | EP | claimed |
| CN-122055379-A | Compounds containing one or more diboronate esters and related insulin analogues | 普罗托莫科技公司 | 2026-05-15 | — | — | CN | disclosed |
| EP-4694932-A2 | COMPOUNDS CONTAINING ONE OR MORE DIBORONATES AND RELATED INSULIN ANALOGS | Protomer Technologies Inc. (US) | 2026-02-18 | — | — | EP | disclosed |
| US-20250249074-A1 | GLUCOSE RESPONSIVE INSULINS | PROTOMER TECHNOLOGIES INC. | 2025-08-07 | — | — | US | disclosed |
| CN-120081711-A | Method for preparing liquid fertilizer from lincomycin and ivermectin waste liquid | 宁夏泰胜生物科技有限公司 | 2025-06-03 | — | — | CN | disclosed |
| CN-119677541-A | Aromatic boron-containing compounds and related insulin analogues | 原聚体科技公司 | 2025-03-21 | — | — | CN | disclosed |
| CN-119661374-A | Method for preparing (1R, 2S) -2, 6-dimethyl-1-indene amine by using chiral amino acid resolving agent | 中国科学院大连化学物理研究所 | 2025-03-21 | — | — | CN | disclosed |
| US-5468876-A | Intermediates for the stereoconservative synthesis of 1-substituted (S)-and (R)-2-aminomethylpyrrolidines | AKTIEBOLAGET ASTRA (SE) | 1995-11-21 | — | — | US | disclosed |
| US-5300660-A | Efficient stereoconservative synthesis of 1-substituted (S)- and (R)-2-aminomethylpyrrolidines and intermediates thereto | ASTRA LAKEMEDEL AKTIEBOLAG (SE) | 1994-04-05 | — | — | US | disclosed |
| CN-1021044-C | PREPARATION METHOD FOR ACIDOPHOBIC-METHYL PROPYL PROLINE INTERMEDIATE D-3-ACETYLSULFURIC-2-METHYL-PROPIONY-L-PROLINE | SHANGHAI MEDICAL INDUSTRY INST (CN) | 1993-06-02 | — | — | CN | disclosed |
| EP-0253785-B1 | EFFICIENT STEREOCONSERVATIVE SYNTHESES OF 1-SUBSTITUTED (S)- AND (R)-2-AMINOMETHYLPYRROLIDINES AND INTERMEDIATES THEREIN | ASTRA LAKEMEDEL AKTIEBOLAG (SE) | 1992-11-11 | — | — | EP | disclosed |
| EP-0270596-A1 | A STEREOCONSERVATIVE SYNTHESIS OF 1-SUBSTITUTED (S)- AND (R)-2-AMINOMETHYLPYRROLIDINES AND INTERMEDIATES THERETO | ASTRA LAKEMEDEL AKTIEBOLAG (SE) | 1988-06-15 | — | — | EP | disclosed |
| WO-1987007271-A1 | A STEREOCONSERVATIVE SYNTHESIS OF 1-SUBSTITUTED (S)- AND (R)-2-AMINOMETHYLPYRROLIDINES AND INTERMEDIATES THERETO | Astra Läkemedel Aktiebolag (SE) | 1987-12-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250249074-A1 | GLUCOSE RESPONSIVE INSULINS | GLP1R, GPR119, IAPP | LMNA 4196/4885KCNK3 4106/4885NR1I2 1374/4885 |
| US-20150353619-A1 | Non-Canonical Insulins and Their Uses | IAPP, IDE, INSR | LMNA 1531/4885KCNK3 3781/4885NR1I2 3403/4885 |
| US-20180251486-A1 | LINCOMYCIN BIOSYNTHETIC INTERMEDIATES, METHOD FOR PREPARATION, AND USE THEREOF | COASY, DHPS, DCXR | LMNA 188/4885KCNK3 3920/4885NR1I2 2826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.