Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | LDHA | P00338 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3329935 | 0.88 | ALOX15 (0.53) | KDM4EALDH1A1HPGDNPSR1CYP1A2 | |
| SCHEMBL3329937 | 0.86 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDNPSR1CYP1A2 | |
| SCHEMBL3325492 | 0.82 | KDM4E (0.56) | KDM4EALDH1A1HPGDNPSR1CYP1A2 | |
| SCHEMBL5222960 | 0.81 | HSD17B10 (0.49) | KDM4EALDH1A1HPGDTSHRGAA | |
| SCHEMBL5479382 | 0.79 | KDM4E (0.50) | KDM4EALDH1A1HPGDNPSR1CYP1A2 | |
| SCHEMBL5476494 | 0.79 | FFAR3 (0.54) | KDM4EALDH1A1HPGDNPSR1CYP1A2 | |
| SCHEMBL5480594 | 0.78 | KDM4E (0.42) | KDM4EALDH1A1HPGDNPSR1CYP1A2 | |
| SCHEMBL5478351 | 0.78 | ALDH1A1 (0.52) | KDM4EALDH1A1HPGDNPSR1CYP1A2 | |
| SCHEMBL5479493 | 0.78 | KDM4E (0.47) | KDM4EALDH1A1HPGDNPSR1CYP1A2 | |
| SCHEMBL4251720 | 0.77 | KDM4E (0.66) | KDM4EALDH1A1HPGDNPSR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814554-A1 | CERTAIN COMPOUNDS, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2007-08-08 | — | — | EP | claimed |
| US-20060116369-A1 | Certain compounds, compositions, and methods | CYTOKINETICS, INC. | 2006-06-01 | — | — | US | claimed |
| WO-2006047537-A1 | CERTAIN COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2006-05-04 | — | — | WO | claimed |
| US-20060116369-A1 | Certain compounds, compositions, and methods | CYTOKINETICS, INC. | 2006-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116369-A1 | Certain compounds, compositions, and methods | PCNA, MKI67, TP53 | KDM4E 4051/4885ALDH1A1 791/4885HPGD 219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.