Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5227544 | 0.87 | MAPT (0.36) | MAPTKCNH2PTGDR2 | |
| SCHEMBL5229156 | 0.86 | P2RX7 (0.36) | MAPTKCNH2PTGDR2 | |
| SCHEMBL5226744 | 0.83 | MAPT (0.37) | MAPTKCNH2PTGDR2 | |
| SCHEMBL509197 | 0.82 | KCNH2 (0.37) | MAPTKCNH2PTGDR2 | |
| SCHEMBL509302 | 0.82 | PTGDR2 (0.38) | MAPTKCNH2PTGDR2 | |
| SCHEMBL509176 | 0.81 | KCNH2 (0.39) | MAPTKCNH2PTGDR2 | |
| SCHEMBL5229824 | 0.80 | MAPT (0.39) | MAPTKCNH2PTGDR2 | |
| SCHEMBL5229464 | 0.79 | NPSR1 (0.38) | MAPT | |
| SCHEMBL509505 | 0.78 | MAPT (0.37) | MAPTKCNH2PTGDR2 | |
| SCHEMBL509737 | 0.78 | RAB9A (0.37) | MAPTKCNH2PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377556-B1 | PYRAZOLE DERIVATIVES FOR TREATING HIV | PFIZER LTD (GB) | 2007-04-04 | — | — | EP | claimed |