Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9000042 | 0.88 | ALOX15 (0.32) | — | |
| SCHEMBL7475234 | 0.80 | — | — | |
| SCHEMBL9801221 | 0.79 | SOS1 (0.32) | KEAP1SMN1; SMN2 | |
| SCHEMBL5245237 | 0.78 | SOS1 (0.34) | — | |
| SCHEMBL11045457 | 0.77 | SOS1 (0.31) | — | |
| SCHEMBL3320955 | 0.74 | TSHR (0.35) | — | |
| SCHEMBL11790753 | 0.70 | — | — | |
| SCHEMBL1082344 | 0.69 | — | — | |
| SCHEMBL24936392 | 0.67 | ALOX15 (0.31) | — | |
| SCHEMBL6380836 | 0.67 | SOS1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1792897-A2 | Intercalators having affinity for DNA and methods of use | Abbott Laboratories (US) | 2007-06-06 | — | — | EP | disclosed |
| EP-1411047-A1 | Intercalators having affinity for DNA and methods of use | ABBOTT LABORATORIES (US) | 2004-04-21 | — | — | EP | disclosed |
| US-6015902-A | Intercalators having affinity for DNA and methods of use | ABBOTT LABORATORIES (US) | 2000-01-18 | — | — | US | disclosed |
| US-5808077-A | LABELING, INSERTION, ANALYSIS | ABBOTT LABORATORIES (US) | 1998-09-15 | — | — | US | disclosed |
| US-5599932-A | AMINO-SUBSTITUTED PHENANTHRIDINE DERIVATIVES | ABBOTT LABORATORIES (US) | 1997-02-04 | — | — | US | disclosed |
| EP-0706515-A1 | INTERCALATORS HAVING AFFINITY FOR DNA AND METHODS OF USE | Abbott Laboratories (US) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995001341-A1 | INTERCALATORS HAVING AFFINITY FOR DNA AND METHODS OF USE | ABBOTT LABORATORIES (US) | 1995-01-12 | — | — | WO | disclosed |