SCHEMBL5245237

SCHEMBL5245237

CCCN1CCNCC1(N)N

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SOS1 Q07889 1/20 0.34
SOS2 Q07890 1/20 0.34
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3320955 0.83 TSHR (0.35) SOS1SOS2TSHR
SCHEMBL28273821 0.82 SOS1 (0.33) SOS1SOS2
SCHEMBL9000042 0.82 ALOX15 (0.32) SOS1SOS2
SCHEMBL7026672 0.79 SOS1 (0.32) SOS1SOS2
SCHEMBL5227154 0.78 KEAP1 (0.31)
SCHEMBL7449892 0.78 SOS1 (0.35) SOS1SOS2TSHR
SCHEMBL11722966 0.76 SOS1 (0.34) SOS1SOS2TSHR
SCHEMBL19362277 0.76 SOS1 (0.34) SOS1SOS2TSHR
SCHEMBL10995764 0.74 SOS1 (0.33) SOS1SOS2
SCHEMBL6012604 0.73 SOS1 (0.44) SOS1SOS2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1828290-A1 POLYETHER BLOCK AMIDE FOAM Arkema France (FR) 2007-09-05 EP disclosed
WO-2006045513-A1 POLYETHER BLOCK AMIDE FOAM ARKEMA FRANCE (FR) 2006-05-04 WO disclosed
US-7014919-B2 Polyamide-based transparent composition RKEMA (FR) 2006-03-21 US disclosed
US-20020173596-A1 Polyamide-based transparent composition ATOFINA (FR) 2002-11-21 US disclosed
US-4208340-A UV ABSORBERS, INSECTICIDES AND ANTIOXIDANT INTERMEDIATES STANDARD OIL COMPANY (INDIANA) (US) 1980-06-17 US disclosed