⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5227255 | 0.70 | — | — | |
| SCHEMBL13108811 | 0.69 | — | — | |
| SCHEMBL15836958 | 0.64 | — | — | |
| SCHEMBL20910 | 0.64 | — | — | |
| SCHEMBL27918809 | 0.64 | ALDH1A1 (0.44) | — | |
| SCHEMBL469386 | 0.63 | ALDH1A1 (0.72) | — | |
| SCHEMBL1588979 | 0.63 | ALDH1A1 (0.55) | — | |
| SCHEMBL28172041 | 0.62 | — | — | |
| SCHEMBL2001221 | 0.60 | — | — | |
| SCHEMBL15671160 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101203142-A | Aromatic amides and ureas and their uses as sweet and/or delicate flavor modifiers, flavouring agents and taste enhancers | SENOMYX INC (US) | 2008-06-18 | — | — | CN | claimed |
| CN-110023304-A | Calpain regulator and its therapeutical uses | 布莱德治疗公司 | 2019-07-16 | — | — | CN | disclosed |
| CN-105308036-B | The Compounds and methods for and its indication adjusted for kinases | 普莱希科公司 | 2019-06-21 | — | — | CN | disclosed |
| CN-108137585-A | Heterocyclic compounds and their use | 普莱希科公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-107548394-A | Adjust the solid form of the compound of kinases | 普莱希科公司 | 2018-01-05 | — | — | CN | disclosed |
| CN-104356127-B | Containing the double heterocyclic amides of N and its application as immunodepressant | 重庆理工大学 | 2017-06-16 | — | — | CN | disclosed |
| US-20160031877-A1 | KINASE INHIBITORS, PRODRUG FORMS THEREOF AND THEIR USE IN THERAPY | AUCKLAND UNISERVICES LIMITED (NZ) | 2016-02-04 | — | — | US | disclosed |
| US-9101632-B2 | Kinase inhibitors, prodrug forms thereof and their use in therapy | AUCKLAND UNISERVICES LIMITED (NZ) | 2015-08-11 | — | — | US | disclosed |
| US-20120202832-A1 | KINASE INHIBITORS, PRODRUG FORMS THEREOF AND THEIR USE IN THERAPY | AUCKLAND UNISERVICES LIMITED (NZ) | 2012-08-09 | — | — | US | disclosed |
| CN-101754955-A | Indazole, benzisoxazole and benzisothiazole compounds as protein kinase inhibitors | ABBOTT LAB | 2010-06-23 | — | — | CN | disclosed |
| EP-1355887-B1 | PYRIMIDINE ACYCLONUCLEOSIDE DERIVATIVES, PREPARATION METHOD AND USE THEREOF | UNIV GENEVE (CH) | 2007-08-15 | — | — | EP | disclosed |
| US-6911450-B1 | Pyrimidine acyclonucleoside derivatives, preparation method and use thereof | UNIVERSITE DE GENEVE (CH) | 2005-06-28 | — | — | US | disclosed |
| EP-1355887-A1 | PYRIMIDINE ACYCLONUCLEOSIDE DERIVATIVES, PREPARATION METHOD AND USE THEREOF | UNIVERSITE DE GENEVE (CH) | 2003-10-29 | — | — | EP | disclosed |
| WO-2002060880-A1 | PYRIMIDINE ACYCLONUCLEOSIDE DERIVATIVES, PREPARATION METHOD AND USE THEREOF | UNIVERSITE DE GENEVE (CH) | 2002-08-08 | — | — | WO | disclosed |