Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.46 |
| ▸ | CBX7 | O95931 | 1/20 | 0.46 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.46 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.46 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28265104 | 0.85 | MEN1 (0.52) | KMT2AMEN1TSHRALOX12ALDH1A1 | |
| SCHEMBL6958446 | 0.82 | KMT2A (0.53) | KMT2AMEN1TSHRALOX12ALDH1A1 | |
| SCHEMBL5337208 | 0.82 | BCHE (0.49) | KMT2AMEN1TSHRALOX12ALDH1A1 | |
| SCHEMBL28263925 | 0.81 | TSHR (0.47) | KMT2AMEN1TSHRALOX12ALDH1A1 | |
| SCHEMBL28265078 | 0.81 | MEN1 (0.46) | KMT2AMEN1TSHRALOX12ALDH1A1 | |
| SCHEMBL17363875 | 0.78 | KMO (0.51) | KMT2AMEN1TSHRPOLBHTT | |
| SCHEMBL17363662 | 0.78 | TSHR (0.42) | KMT2AMEN1TSHRALDH1A1CBX7 | |
| SCHEMBL17363932 | 0.78 | CHRM5 (0.41) | TSHRALDH1A1HTTKDM4EGAA | |
| SCHEMBL2748218 | 0.77 | TSHR (0.53) | KMT2AMEN1TSHRALOX12ALDH1A1 | |
| SCHEMBL30581468 | 0.77 | TSHR (0.53) | KMT2AMEN1TSHRALOX12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104557907-A | Method for preparing azasetron hydrochloride | SICHUAN HAIRONG PHARMACEUTICAL CO LTD YANGTZE RIVER PHARMACEUTICAL GROUP | 2015-04-29 | — | — | CN | claimed |
| CN-104557906-A | Method for preparing azasetron hydrochloride | SICHUAN HAIRONG PHARMACEUTICAL CO LTD YANGTZE RIVER PHARMACEUTICAL GROUP | 2015-04-29 | — | — | CN | claimed |
| EP-3717477-A1 | NEW HETEROCYCLIC COMPOUNDS | H. Hoffnabb-La Roche Ag (CH) | 2020-10-07 | — | — | EP | disclosed |
| CN-104557907-A | Method for preparing azasetron hydrochloride | SICHUAN HAIRONG PHARMACEUTICAL CO LTD YANGTZE RIVER PHARMACEUTICAL GROUP | 2015-04-29 | — | — | CN | disclosed |
| CN-104557906-A | Method for preparing azasetron hydrochloride | SICHUAN HAIRONG PHARMACEUTICAL CO LTD YANGTZE RIVER PHARMACEUTICAL GROUP | 2015-04-29 | — | — | CN | disclosed |
| US-7312213-B2 | Substituted benzo[e][1,4]oxazino[3,2-g]isoindole compounds | LES LABORATORIES SERVIER (FR) | 2007-12-25 | — | — | US | disclosed |
| EP-1556387-B1 | SUBSTITUTED BENZOL E| 1,4| OXAZINO 3,2-G| ISOINDOLE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2007-04-04 | — | — | EP | disclosed |
| EP-1587810-B1 | NOVEL SUBSTITUTED 1,4|BENZODIOXINO 2,3-E|ISOINDOLE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2006-11-08 | — | — | EP | disclosed |
| US-20060003997-A1 | Substituted benzo[e] [1,4] oxazino [3,2-g] isoindole compounds | LES LABORATOIRES SERVIER (FR) | 2006-01-05 | — | — | US | disclosed |
| EP-1587810-A1 | NOVEL SUBSTITUTED 1,4]BENZODIOXINO 2,3-E]ISOINDOLE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2005-10-26 | — | — | EP | disclosed |
| EP-1556387-A1 | SUBSTITUTED BENZOL E] 1,4] OXAZINO 3,2-G] ISOINDOLE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Les Laboratoires Servier (FR) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004037831-A1 | NOVEL SUBSTITUTED[1,4]BENZODIOXINO[2,3-E]ISOINDOLE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2004-05-06 | — | — | WO | disclosed |
| WO-2004037829-A1 | NOVEL BENZOXAZOLE OR OXAZOLOPYRIDINE COMPOUNDS, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2004-05-06 | — | — | WO | disclosed |
| WO-2004037830-A1 | SUBSTITUTED BENZOL[E] [1,4] OXAZINO[3,2-G] ISOINDOLE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2004-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060003997-A1 | Substituted benzo[e] [1,4] oxazino [3,2-g] isoindole compounds | H1-3, H1-0, H1-2 | KMT2A 2620/4885MEN1 1775/4885TSHR 536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.