Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | CBX7 | O95931 | 2/20 | 0.46 |
| ▸ | CDYL2 | Q8N8U2 | 2/20 | 0.46 |
| ▸ | CDYL | Q9Y232 | 2/20 | 0.46 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28265104 | 0.86 | MEN1 (0.52) | CBX7CDYL2CDYLCDY1; CDY1BALDH1A1 | |
| SCHEMBL28265078 | 0.82 | MEN1 (0.46) | CBX7CDYL2CDYLCDY1; CDY1BALDH1A1 | |
| SCHEMBL28263925 | 0.82 | TSHR (0.47) | CBX7CDYL2CDYLCDY1; CDY1BALDH1A1 | |
| SCHEMBL5227565 | 0.82 | KMT2A (0.50) | CBX7CDYL2CDYLCDY1; CDY1BALDH1A1 | |
| SCHEMBL5418613 | 0.80 | ALDH1A1 (0.39) | BCHEALDH1A1TSHRUSP2MAPT | |
| SCHEMBL30687393 | 0.78 | NOTUM (0.59) | BCHEALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL5808642 | 0.78 | NOTUM (0.59) | BCHEALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL18964807 | 0.75 | NOTUM (0.45) | BCHEALDH1A1KMT2ALMNAPOLB | |
| SCHEMBL6958446 | 0.75 | KMT2A (0.53) | CBX7CDYL2CDYLCDY1; CDY1BALDH1A1 | |
| SCHEMBL9608993 | 0.73 | BCHE (0.53) | BCHEALDH1A1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7202255-B2 | Substituted [1,4] benzodioxino[2,3-e] isoindole derivatives, method for preparing and pharmaceutical compositions containing same | LES LABORATOIRES SERVIER (FR) | 2007-04-10 | — | — | US | disclosed |
| US-20060040930-A1 | Novel substituted [1,4] benzodioxino[2,3-e] isoindole derivatives, method for preparing and pharmaceutical compositions containing same | LES LABORATOIRES SERVIER (FR) | 2006-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060040930-A1 | Novel substituted [1,4] benzodioxino[2,3-e] isoindole derivatives, method for preparing and pharmaceutical compositions containing same | CYP11B2, CYP2F1, CYP3A43 | BCHE 997/4885CBX7 874/4885CDYL2 1073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.