Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14045705 | 0.91 | ALDH1A1 (0.52) | SLC18A3OPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL8283980 | 0.84 | ALDH1A1 (0.46) | SLC18A3OPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL5651526 | 0.83 | GBA1 (0.56) | ALDH1A1LMNABLMSMN1; SMN2CARM1 | |
| SCHEMBL1191857 | 0.83 | HTT (0.54) | SLC18A3ALDH1A1LMNABLMSMN1; SMN2 | |
| SCHEMBL4686478 | 0.83 | CARM1 (0.47) | SLC18A3OPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL18890807 | 0.82 | LSS (0.52) | OPRM1LMNACARM1PRMT6TSHR | |
| SCHEMBL5722096 | 0.81 | OPRM1 (0.61) | OPRM1OPRD1OPRK1G6PC1HSD17B10 | |
| SCHEMBL12126132 | 0.79 | OPRM1 (0.54) | OPRM1OPRD1OPRK1TSHRHSD17B10 | |
| SCHEMBL10039132 | 0.79 | OPRM1 (0.54) | SLC18A3OPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL17346290 | 0.78 | OPRM1 (0.43) | SLC18A3OPRM1OPRD1OPRK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11718643-B2 | Multimodal anion exchange matrices | CYTIVA BIOPROCESS R&D AB (SE) | 2023-08-08 | — | — | US | disclosed |
| US-11718643-B2 | Multimodal anion exchange matrices | CYTIVA BIOPROCESS R&D AB (SE) | 2023-08-08 | — | — | US | disclosed |
| US-10815269-B2 | Multimodal anion exchange matrices | GE HEALTHCARE BIOPROCESS R&D AB (SE) | 2020-10-27 | — | — | US | disclosed |
| US-20190023735-A1 | Multimodal Anion Exchange Matrices | GE HEALTHCARE BIOPROCESS R&D AB (SE) | 2019-01-24 | — | — | US | disclosed |
| CN-102659718-B | Prepare the method for cyclopropyl-amide derivatives | JANSSEN PHARMACEUTICA N. V. (BE) | 2015-11-25 | — | — | CN | disclosed |
| US-20150299248-A1 | Multimodal Anion Exchange Matrices | GE Healtchare Bio-Sciences AB (SE) | 2015-10-22 | — | — | US | disclosed |
| US-20150299248-A1 | Multimodal Anion Exchange Matrices | GE Healtchare Bio-Sciences AB (SE) | 2015-10-22 | — | — | US | disclosed |
| US-20120283433-A1 | NOVEL PROCESSES FOR THE PREPARATION OF CYCLOPROPYL-AMIDE DERIVATIVES | MANI NEELAKANDHA S (US) | 2012-11-08 | — | — | US | disclosed |
| US-20120283433-A1 | NOVEL PROCESSES FOR THE PREPARATION OF CYCLOPROPYL-AMIDE DERIVATIVES | MANI NEELAKANDHA S (US) | 2012-11-08 | — | — | US | disclosed |
| US-20120283433-A1 | NOVEL PROCESSES FOR THE PREPARATION OF CYCLOPROPYL-AMIDE DERIVATIVES | MANI NEELAKANDHA S (US) | 2012-11-08 | — | — | US | disclosed |
| US-7728129-B2 | Processes for the preparation of piperazinyl and diazapanyl benzamide derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2010-06-01 | — | — | US | disclosed |
| EP-1951699-A2 | PROCESSES FOR THE PREPARATION OF CYCLOPROPYL-AMIDE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-08-06 | — | — | EP | disclosed |
| US-20070197508-A1 | NOVEL PROCESSES FOR THE PREPARATION OF PIPERAZINYL AND DIAZAPANYL BENZAMIDE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-08-23 | — | — | US | disclosed |
| US-20070197508-A1 | NOVEL PROCESSES FOR THE PREPARATION OF PIPERAZINYL AND DIAZAPANYL BENZAMIDE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-08-23 | — | — | US | disclosed |
| US-20070197508-A1 | NOVEL PROCESSES FOR THE PREPARATION OF PIPERAZINYL AND DIAZAPANYL BENZAMIDE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-08-23 | — | — | US | disclosed |
| US-20070129351-A1 | NOVEL PROCESSES FOR THE PREPARATION OF CYCLOPROPYL-AMIDE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-06-07 | — | — | US | disclosed |
| US-20070129351-A1 | NOVEL PROCESSES FOR THE PREPARATION OF CYCLOPROPYL-AMIDE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-06-07 | — | — | US | disclosed |
| US-20070129351-A1 | NOVEL PROCESSES FOR THE PREPARATION OF CYCLOPROPYL-AMIDE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-06-07 | — | — | US | disclosed |
| WO-2007053386-A2 | PROCESSES FOR THE PREPARATION OF CYCLOPROPYL-AMIDE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-05-10 | — | — | WO | disclosed |
| WO-2007053386-A2 | PROCESSES FOR THE PREPARATION OF CYCLOPROPYL-AMIDE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10815269-B2 | Multimodal anion exchange matrices | H1-3, H1-4, IGF2R | SLC18A3 276/4885OPRM1 55/4885OPRD1 428/4885 |
| US-20070197508-A1 | NOVEL PROCESSES FOR THE PREPARATION OF PIPERAZINYL AND DIAZAPANYL BENZAMIDE DERIVATIVES | HRH2, HRH4, HRH1 | SLC18A3 1211/4885OPRM1 1444/4885OPRD1 1034/4885 |
| US-11718643-B2 | Multimodal anion exchange matrices | H1-3, H1-4, IGF2R | SLC18A3 276/4885OPRM1 55/4885OPRD1 428/4885 |
| US-20150299248-A1 | Multimodal Anion Exchange Matrices | H1-3, H1-4, IGF2R | SLC18A3 276/4885OPRM1 55/4885OPRD1 428/4885 |
| US-20190023735-A1 | Multimodal Anion Exchange Matrices | H1-3, H1-4, IGF2R | SLC18A3 276/4885OPRM1 55/4885OPRD1 428/4885 |
| US-20070129351-A1 | NOVEL PROCESSES FOR THE PREPARATION OF CYCLOPROPYL-AMIDE DERIVATIVES | HRH4, HRH2, HRH1 | SLC18A3 291/4885OPRM1 118/4885OPRD1 116/4885 |
| US-20120283433-A1 | NOVEL PROCESSES FOR THE PREPARATION OF CYCLOPROPYL-AMIDE DERIVATIVES | HRH4, HRH2, HRH1 | SLC18A3 291/4885OPRM1 118/4885OPRD1 116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.