Styrene

Styrene

SCHEMBL522764

C=C(C=Cc1ccccc1)C(=O)OCCCC.C=Cc1ccccc1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.49
TDP1 Q9NUW8 3/20 0.47
TSHR P16473 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
BCHE P06276 6/20 0.45
EGFR P00533 1/20 0.44
HDAC3 O15379 1/20 0.44
ACHE P22303 4/20 0.44
APP P05067 1/20 0.42
CYP3A4 P08684 2/20 0.42
MAPK1 P28482 2/20 0.42
ALDH1A1 P00352 2/20 0.42
TP53 P04637 1/20 0.41
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
HSD17B10 Q99714 1/20 0.41
AKR1B10 O60218 1/20 0.41
AKR1B1 P15121 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29394 0.95 KDM4E (0.53) KDM4ETDP1TSHRL3MBTL1BCHE
Butadiene SCHEMBL10718191 0.94 KDM4E (0.50) KDM4ETDP1TSHRL3MBTL1BCHE
Acrylic Acid SCHEMBL29184857 0.92 KDM4E (0.49) KDM4ETDP1TSHRL3MBTL1BCHE
Maleic Acid SCHEMBL11028703 0.91 KDM4E (0.50) KDM4ETDP1TSHRL3MBTL1BCHE
Styrene SCHEMBL250640 0.90 HCAR2 (0.47) KDM4ETDP1TSHRL3MBTL1BCHE
Methacrylic Acid SCHEMBL390016 0.90 KDM4E (0.49) KDM4ETDP1TSHRL3MBTL1BCHE
SCHEMBL10901969 0.90 TSHR (0.52) KDM4ETDP1TSHRL3MBTL1BCHE
SCHEMBL668688 0.90 TSHR (0.52) KDM4ETDP1TSHRL3MBTL1BCHE
SCHEMBL7457989 0.90 TSHR (0.52) KDM4ETDP1TSHRL3MBTL1BCHE
SCHEMBL9659269 0.89 KDM4E (0.45) KDM4ETDP1TSHRL3MBTL1BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109461910-B Lithium battery positive electrode based on graphene-sulfur composite material and preparation method thereof 浙江大学 2021-04-06 CN claimed
US-20120029139-A1 BLOCK COPOLYMERS HAVING ASSOCIATIVE GROUPS, AND ADHESIVE CONTAINING SAME CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS (FR) 2012-02-02 US claimed
WO-2024117230-A1 PHOTOCURABLE RESIN COMPOSITION, ADHESIVE SHEET, AND METHOD FOR MANUFACTURING LAMINATE 積水化学工業株式会社 2024-06-06 WO disclosed
CN-117466627-A Super wear-resistant ceramic tile and production process thereof 合肥陶陶新材料科技有限公司 2024-01-30 CN disclosed
CN-116444997-B Copolymer modified emulsified asphalt and preparation method thereof 陕西国威沥青新产品有限公司 2023-12-01 CN disclosed
CN-117089303-A Acrylate block copolymer-based hot melt adhesive and preparation method thereof 广州市芳海热熔胶制造有限公司 2023-11-21 CN disclosed
CN-116444997-A Copolymer modified emulsified asphalt and preparation method thereof 陕西国威沥青新产品有限公司 2023-07-18 CN disclosed
CN-114586777-B Prothioconazole and chlorothalonil compound water dispersible granule and preparation method thereof 南京林业大学 2022-11-04 CN disclosed
CN-114631526-B Auxiliary agent for improving rain washing resistance of mancozeb wettable powder and preparation method thereof 南京林业大学 2022-09-30 CN disclosed
CN-114631526-A Auxiliary agent for improving rain wash resistance of mancozeb wettable powder and preparation method thereof 南京林业大学 2022-06-17 CN disclosed
CN-114586777-A Prothioconazole and chlorothalonil compound water dispersible granule and preparation method thereof 南京林业大学 2022-06-07 CN disclosed
US-20080004366-A1 ORGANIC TELLURIUM COMPOUND, PROCESS FOR PRODUCING THE SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER WITH THE SAME, AND POLYMER YAMAGO SHIGERU 2008-01-03 US disclosed
US-7276569-B2 Organic tellurium compound, process for producing the same, living radical polymerization initiator, process for producing polymer with the same, and polymer OTSUKA CHEMICAL CO., LTD. (JP) 2007-10-02 US disclosed
US-20060258826-A1 Atom or group transfer radical polymerization CARNEGIE MELLON UNIVERSITY 2006-11-16 US disclosed
US-7125938-B2 Atom or group transfer radical polymerization CARNEGIE MELLON UNIVERSITY (US) 2006-10-24 US disclosed
US-20050245714-A1 Organic tellurium compound, process for producing the same, living radical polymerization initiator, process for producing polymer with the same, and polymer OTSUKA CHEMICAL CO., LTD. (JP) 2005-11-03 US disclosed
EP-1541550-A1 ORGANIC TELLURIUM COMPOUND, PROCESS FOR PRODUCING THE SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER WITH THE SAME, AND POLYMER Otsuka Chemical Co., Ltd. (JP) 2005-06-15 EP disclosed
US-20040204556-A1 Atom or group transfer radical polymerization MATYJASZEWSKI KRZYSZTOF (US) 2004-10-14 US disclosed
US-6541580-B1 Controlling living polymerization via e.g. polyphosphazene initiators CARNEGIE MELLON UNIVERSITY 2003-04-01 US disclosed
US-6512060-B1 Contacting at least one first molecule comprising one or more radically transferable atoms or groups, and at least one second molecule comprising one or more radically transferable atoms or groups with a system comprising: a transition metal, CARNEGIE MELLON UNIVERSITY 2003-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050245714-A1 Organic tellurium compound, process for producing the same, living radical polymerization initiator, process for producing polymer with the same, and polymer ODC1, TERB1, TTI1 KDM4E 1148/4885TDP1 602/4885TSHR 1738/4885
US-20080004366-A1 ORGANIC TELLURIUM COMPOUND, PROCESS FOR PRODUCING THE SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER WITH THE SAME, AND POLYMER ODC1, TERB1, TTI1 KDM4E 1148/4885TDP1 602/4885TSHR 1738/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.