Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 5/20 | 0.70 |
| ▸ | ANPEP | P15144 | 1/20 | 0.70 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.70 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.70 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 2/20 | 0.51 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | METAP1 | P53582 | 1/20 | 0.47 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | CTSC | P53634 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20474481 | 1.00 | LAP3 (0.70) | LAP3ANPEPRNPEPDNPEPSLC15A1 | |
| SCHEMBL8494993 | 1.00 | LAP3 (0.70) | LAP3ANPEPRNPEPDNPEPSLC15A1 | |
| Hydrochloric Acid SCHEMBL20474460 | 0.98 | LAP3 (0.68) | LAP3ANPEPRNPEPDNPEPSLC15A1 | |
| Hydrochloric Acid SCHEMBL3841335 | 0.98 | LAP3 (0.68) | LAP3ANPEPRNPEPDNPEPSLC15A1 | |
| SCHEMBL3135806 | 0.88 | LAP3 (0.75) | LAP3ANPEPRNPEPDNPEPSLC15A1 | |
| Hydrochloric Acid SCHEMBL4397404 | 0.87 | LAP3 (0.73) | LAP3ANPEPRNPEPDNPEPSLC15A1 | |
| SCHEMBL17097365 | 0.86 | LAP3 (0.68) | LAP3ANPEPRNPEPDNPEPSLC15A1 | |
| SCHEMBL7951029 | 0.86 | LAP3 (0.68) | LAP3ANPEPRNPEPDNPEPSLC15A1 | |
| SCHEMBL8498476 | 0.85 | LAP3 (0.71) | LAP3ANPEPRNPEPDNPEPCSNK1E | |
| SCHEMBL27916353 | 0.85 | LAP3 (0.71) | LAP3ANPEPRNPEPDNPEPCSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0910564-B1 | D-AMINO ACID DERIVED INHIBITORS OF CYSTEINE AND SERINE PROTEASES | CEPHALON INC (US) | 2007-10-31 | — | — | EP | disclosed |
| EP-0938477-A4 | BENZOTHIAZO AND RELATED HETEROCYCLIC GROUP-CONTAINING CYSTEINE AND SERINE PROTEASE INHIBITORS | CEPHALON INC (US) | 1999-12-29 | — | — | EP | disclosed |
| US-5952328-A | MAY BE USED TO ALLEVIATE, MEDIATE, REDUCE AND/OR PREVENT DISORDERS WHICH ARE ASSOCIATED WITH ABNORMAL AND/OR ABERRANT ACTIVITY OF CYSTEINE PROTEASES AND/OR SERINE PROTEASES | CEPHALON, INC. (US) | 1999-09-14 | — | — | US | disclosed |
| EP-0938477-A1 | BENZOTHIAZO AND RELATED HETEROCYCLIC GROUP-CONTAINING CYSTEINE AND SERINE PROTEASE INHIBITORS | CEPHALON, INC. (US) | 1999-09-01 | — | — | EP | disclosed |
| US-5852007-A | Cysteine and serine protease inhibitors containing D-amino acid at the P2 position, methods of making same, and methods of using same | CEPHALON, INC. (US) | 1998-12-22 | — | — | US | disclosed |
| WO-1998021186-A1 | BENZOTHIAZO AND RELATED HETEROCYCLIC GROUP-CONTAINING CYSTEINE AND SERINE PROTEASE INHIBITORS | CEPHALON, INC. (US) | 1998-05-22 | — | — | WO | disclosed |