SCHEMBL5227837

SCHEMBL5227837

[CH2]C(Cl)CCOC(N)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10621795 0.81
SCHEMBL29018747 0.79
SCHEMBL1767372 0.74 CHRNB2 (0.50)
SCHEMBL3094407 0.73
SCHEMBL28294697 0.72 CHRNB2 (0.44)
Ethylene SCHEMBL21679941 0.72 TSHR (0.52)
Formaldehyde SCHEMBL4454552 0.72 TSHR (0.52)
SCHEMBL25235684 0.71
SCHEMBL224100 0.71
SCHEMBL28221889 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1218337-B1 SYNTHESIS OF 3,5,7|-1H-IMIDAZO 1,5-A|IMIDAZOL-2(3H)-ONE COMPOUNDS TORREY PINES INST (US) 2007-10-31 EP disclosed
US-20050112693-A1 Diketodiazacyclic compounds, diazacyclic compounds and combinatorial libraries thereof NEFZI ADEL (US) 2005-05-26 US disclosed
US-6861523-B2 1,3,5- trisubstituted-1,3,5-triazine-2,4,6-trione compounds and libraries TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) 2005-03-01 US disclosed
US-6809202-B2 SYNTHETIC PEPTIDES TORREY PINES INSTITUTE FOR MOLECULAR STUDIES 2004-10-26 US disclosed
US-6664282-B2 For preparing and using libraries of compounds as well as individual compounds of the libraries; for screening compounds for combinatorial chemistry TORREY PINES INSTITUTE FOR MOLECULAR STUDIES 2003-12-16 US disclosed
US-20030186320-A1 1,3,5- trisubstituted-1,3,5-triazine-2,4,6-trione compounds and libraries TORREY PINES INSTITUTE FOR MOLECULAR STUDIES 2003-10-02 US disclosed
US-20030120066-A1 Synthetic peptides NEFZI ADEL (US) 2003-06-26 US disclosed
US-6545032-B1 Combinatorial libraries TORREY PINES INSTITUTE FOR MOLECULAR STUDIES 2003-04-08 US disclosed
US-20020193608-A1 Synthesis of [3,5,7]--1H-imidazo [1,5-a]imidazol-2 (3H)- one compounds ELABDELLAOUI HASSAN M (US) 2002-12-19 US disclosed
EP-1181279-A4 DIKETODIAZACYCLIC COMPOUNDS, DIAZACYCLIC COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF TORREY PINES INST (US) 2002-09-25 EP disclosed
WO-1997010221-A1 SYNTHESIS OF QUINAZOLINONE LIBRARIES TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) 1997-03-20 WO disclosed
US-5272265-A 3-(substituted or unsubstituted) thiazolo-1-carba (1-dethia)cephems ELI LILLY AND COMPANY (US) 1993-12-21 US disclosed
US-5179088-A Administering bactericides ELI LILLY AND COMPANY (US) 1993-01-12 US disclosed
EP-0445925-A1 1-Carba(dethia)caphalosporin antibiotics ELI LILLY AND COMPANY (US) 1991-09-11 EP disclosed
US-5030708-A Methine benzindole dyes as comonomers in polyesters; nontoxic; heat resistance; food and beverage containers and packaging; color intensity EASTMAN KODAK COMPANY (US) 1991-07-09 US disclosed
US-5011938-A Antimicrobials ELI LILLY AND COMPANY (US) 1991-04-30 US disclosed
US-4940718-A BACTERICIDES ELI LILLY AND COMPANY (US) 1990-07-10 US disclosed
US-4876251-A ANTIBIOTICS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1989-10-24 US disclosed
EP-0310214-A2 7-Substituted bicyclic pyrazolidinones ELI LILLY AND COMPANY (US) 1989-04-05 EP disclosed
EP-0249909-A1 Tricyclic penam compounds, their production and their use Takeda Chemical Industries, Ltd. (JP) 1987-12-23 EP disclosed