Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5227837 | 0.72 | — | — | |
| SCHEMBL28221084 | 0.72 | — | — | |
| SCHEMBL10621795 | 0.72 | — | — | |
| SCHEMBL29018747 | 0.70 | — | — | |
| SCHEMBL1767372 | 0.69 | CHRNB2 (0.50) | CHRNB2CHRNA4CHRNB4CHRNA3TSHR | |
| SCHEMBL245045 | 0.69 | THRB (0.61) | CHRNB2CHRNA4CHRNB4CHRNA3TSHR | |
| SCHEMBL21292110 | 0.69 | THRB (0.61) | CHRNB2CHRNA4CHRNB4CHRNA3TSHR | |
| SCHEMBL31418363 | 0.68 | — | — | |
| SCHEMBL224100 | 0.68 | — | — | |
| SCHEMBL20607652 | 0.67 | TSHR (0.43) | CHRNB2CHRNA4CHRNB4CHRNA3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109880021-A | Polymer and preparation method thereof, ROS response type siRNA nano-micelle and its application | 河南大学 | 2019-06-14 | — | — | CN | disclosed |