Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CDYL2 | Q8N8U2 | 4/20 | 0.40 |
| ▸ | CDYL | Q9Y232 | 4/20 | 0.40 |
| ▸ | CBX7 | O95931 | 3/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5232441 | 0.92 | GAA (0.40) | HRH3POLBGAATSHRCDYL2 | |
| SCHEMBL5238339 | 0.89 | MAPK1 (0.42) | POLBGAAALDH1A1 | |
| SCHEMBL2996472 | 0.88 | POLB (0.42) | HRH3POLBGAATSHRCDYL2 | |
| SCHEMBL5234525 | 0.82 | SLC8A1 (0.33) | TACR1 | |
| SCHEMBL5232300 | 0.82 | CYP2D6 (0.33) | — | |
| SCHEMBL5230063 | 0.81 | EGFR (0.41) | GAACDYL2CDYLCBX7CDY1; CDY1B | |
| SCHEMBL5234725 | 0.81 | EGFR (0.42) | ALDH1A1 | |
| SCHEMBL5232857 | 0.80 | FKBP1A (0.38) | POLBALDH1A1 | |
| SCHEMBL5236137 | 0.80 | GRIN1 (0.46) | POLBGAAALDH1A1 | |
| SCHEMBL2996646 | 0.80 | GAA (0.42) | HRH3POLBGAATSHRCDYL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664059-B1 | THIENOPYRROLES AS ANTIVIRAL AGENTS | ANGELETTI P IST RICHERCHE BIO (IT) | 2007-09-12 | — | — | EP | claimed |