Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5234725 | 0.93 | EGFR (0.42) | GRIN1GRIN2BPTGS2USP2RAB9A | |
| SCHEMBL5230063 | 0.92 | EGFR (0.41) | GRIN1GRIN2BPTGS2TP53HSD17B10 | |
| SCHEMBL5238339 | 0.91 | MAPK1 (0.42) | GRIN1GRIN2BPTGS2USP2NPC1 | |
| SCHEMBL5230369 | 0.90 | ALDH1A1 (0.38) | GRIN1GRIN2BPTGS2KDM4EALDH1A1 | |
| SCHEMBL424159 | 0.89 | GRIN1 (0.46) | GRIN1GRIN2BPTGS2USP2NPC1 | |
| SCHEMBL5231149 | 0.89 | GRIN2B (0.39) | GRIN1GRIN2BPTGS2NPC1RAB9A | |
| SCHEMBL5233368 | 0.88 | LMNA (0.39) | GRIN1GRIN2BPOLBGAAL3MBTL1 | |
| SCHEMBL5232857 | 0.86 | FKBP1A (0.38) | GRIN2BNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL5434937 | 0.80 | PTGS2 (0.46) | GRIN1GRIN2BPTGS2USP2NPC1 | |
| SCHEMBL2996624 | 0.80 | MAPK1 (0.44) | GRIN2BUSP2NPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664059-B1 | THIENOPYRROLES AS ANTIVIRAL AGENTS | ANGELETTI P IST RICHERCHE BIO (IT) | 2007-09-12 | — | — | EP | claimed |