⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3140755 | 0.84 | — | — | |
| SCHEMBL2246634 | 0.84 | CYP1A2 (0.31) | — | |
| SCHEMBL7354628 | 0.82 | SIGMAR1 (0.32) | — | |
| SCHEMBL24197652 | 0.78 | ESR2 (0.50) | — | |
| SCHEMBL240852 | 0.78 | ESR2 (0.50) | — | |
| SCHEMBL5733 | 0.78 | — | — | |
| SCHEMBL321011 | 0.77 | — | — | |
| SCHEMBL11636554 | 0.77 | CYP1A2 (0.36) | — | |
| SCHEMBL79061 | 0.73 | — | — | |
| SCHEMBL80485 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 471 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510561-A | Tylosin derivative and preparation method and application thereof | 中国农业科学院饲料研究所 | 2024-02-06 | — | — | CN | claimed |
| US-11234987-B2 | Isoxazole compounds as inhibitors of heat shock proteins | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2022-02-01 | — | — | US | claimed |
| EP-3148995-B1 | 6-SUBSTITUTED-3H-1,3-BENZOTHIAZOL-2-ONE COMPOUNDS AS TARP-GAMMA 8 DEPENDENT AMPA RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2020-09-23 | — | — | EP | claimed |
| US-10413550-B2 | Isoxazole compounds as inhibitors of heat shock proteins | THE INSTITUTE OF CANCER RESEARCH (GB) | 2019-09-17 | — | — | US | claimed |
| CN-106459027-B | 6-substituted-3H-1, 3-benzothiazol-2-one compounds as TARP-gamma 8 dependent AMPA receptor antagonists | 伊莱利利公司 | 2019-04-02 | — | — | CN | claimed |
| US-9718793-B2 | Isoxazole compounds as inhibitors of heat shock proteins | VERNALIS (R&D) LTD. (GB) | 2017-08-01 | — | — | US | claimed |
| US-20170049781-A1 | HSP90 INHIBITOR COMBINATIONS | NOVARTIS AG (CH) | 2017-02-23 | — | — | US | claimed |
| CN-106459027-A | 6-substituted-3H-1, 3-benzothiazol-2-one compounds as TARP-gamma 8 dependent AMPA receptor antagonists | 伊莱利利公司 | 2017-02-22 | — | — | CN | claimed |
| EP-2016058-B1 | INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2016-01-06 | — | — | EP | claimed |
| US-20150209362-A1 | PHARMACEUTICAL COMBINATIONS COMPRISING A PYRIDO [4,3-D] PYRIMIDINE DERIVED HSP90-INHIBITOR AND A HER2 INHIBITOR | NOVARTIS AG (CH) | 2015-07-30 | — | — | US | claimed |
| EP-0734383-A1 | CYCLIC AMIDE DERIVATIVES AS NEUROKININ A ANTAGONISTS | ZENECA LIMITED (GB) | 1996-10-02 | — | — | EP | claimed |
| EP-0680962-A2 | Heterocyclic compounds | ZENECA LIMITED (GB) | 1995-11-08 | — | — | EP | claimed |
| WO-1995016682-A1 | CYCLIC AMIDE DERIVATIVES AS NEUROKININ A ANTAGONISTS | ZENECA LIMITED (GB) | 1995-06-22 | — | — | WO | claimed |
| EP-0482119-A1 | INTERCALATING AGENTS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1992-04-29 | — | — | EP | claimed |
| WO-1991000265-A1 | INTERCALATING AGENTS | CANCER RESEARCH TECHNOLOGY LTD. (GB) | 1991-01-10 | — | — | WO | claimed |
| US-4925849-A | DIURETICS, HYPOTENSIVE AGENTS, CARIOTONIC AGENTS AND ANTIEDEMIC AGENTS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-05-15 | — | — | US | claimed |
| EP-0299209-A2 | Pyrazolopyridine compound and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-01-18 | — | — | EP | claimed |
| US-4234602-A | ANTIINFLAMMATORY AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1980-11-18 | — | — | US | claimed |
| US-4179558-A | ANITINFLAMMATORY AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1979-12-18 | — | — | US | claimed |
| US-3957766-A | BACTERIOSTATS, BACTERICIDES | BOEHRINGER MANNHEIM G.M.B.H. (DT) | 1976-05-18 | — | — | US | claimed |