Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1152262 | 0.93 | CA1 (0.31) | CA1CA2KDM4ENPC1PABPC1 | |
| Hydrochloric Acid SCHEMBL1152259 | 0.93 | CA1 (0.31) | CA1CA2KDM4ENPC1PABPC1 | |
| SCHEMBL839121 | 0.91 | CA1 (0.32) | CA1CA2KDM4ENPC1PABPC1 | |
| SCHEMBL483865 | 0.91 | CA1 (0.32) | CA1CA2KDM4ENPC1PABPC1 | |
| Hydrochloric Acid SCHEMBL5225789 | 0.87 | CA1 (0.31) | CA1CA2KDM4ENPC1PABPC1 | |
| SCHEMBL839455 | 0.87 | KDM4E (0.42) | CA1CA2KDM4ENPC1PABPC1 | |
| Hydrochloric Acid SCHEMBL5222140 | 0.86 | CA1 (0.30) | CA1CA2 | |
| Hydrochloric Acid SCHEMBL5222333 | 0.85 | CA1 (0.31) | CA1CA2 | |
| Hydrochloric Acid SCHEMBL4805980 | 0.81 | ESR1 (0.32) | KDM4E | |
| Hydrochloric Acid SCHEMBL4804844 | 0.80 | POLB (0.31) | CA1CA2PABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1548006-B1 | Synthesis of tetraazapentamethine derivatives, keratin fibers dyeing process which uses such synthesis | OREAL (FR) | 2007-09-05 | — | — | EP | claimed |