Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA4 | P22748 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28788231 | 0.75 | CA1 (0.45) | CA1CA2CA4CA9KMT2A | |
| SCHEMBL29720703 | 0.73 | CA2 (0.43) | CA1CA2CA4CA9KMT2A | |
| SCHEMBL29720620 | 0.70 | F10 (0.41) | CA1CA2CA4CA9GAA | |
| SCHEMBL6199459 | 0.70 | F10 (0.57) | F10F2 | |
| Hydrochloric Acid SCHEMBL6196801 | 0.70 | F10 (0.59) | F10F2 | |
| SCHEMBL752706 | 0.68 | LMNA (0.68) | KMT2ALMNAGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL3713826 | 0.68 | SMO (0.52) | CA1CA2CA4CA9KMT2A | |
| SCHEMBL3715156 | 0.68 | SMO (0.52) | CA1CA2CA4CA9KMT2A | |
| SCHEMBL11948542 | 0.67 | CA1 (0.51) | CA1CA2CA4CA9HTT | |
| SCHEMBL26673632 | 0.67 | MAPT (0.53) | KMT2ALMNAGAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200824-B1 | SOLID PHASE SYNTHESIS OF N,N-DISUBSTITUTED DIAZACYCLOALKYLCARBOXY DERIVATIVES | AVENTIS PHARMA INC (US) | 2007-04-25 | — | — | EP | disclosed |
| US-7138526-B1 | Solid phase synthesis of n,n-disubstituted diazacycloalkylcarboxy derivatives | AVENTIS PHARMACEUTICALS INC. (US) | 2006-11-21 | — | — | US | disclosed |
| EP-1200824-A4 | SOLID PHASE SYNTHESIS OF N,N-DISUBSTITUTED DIAZACYCLOALKYLCARBOXY DERIVATIVES | AVENTIS PHARM PROD INC (US) | 2003-03-12 | — | — | EP | disclosed |
| EP-1200824-A1 | SOLID PHASE SYNTHESIS OF N,N-DISUBSTITUTED DIAZACYCLOALKYLCARBOXY DERIVATIVES | Aventis Pharmaceuticals Products Inc. (US) | 2002-05-02 | — | — | EP | disclosed |
| WO-2000077519-A1 | SOLID PHASE SYNTHESIS OF N,N-DISUBSTITUTED DIAZACYCLOALKYLCARBOXY DERIVATIVES | AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) | 2000-12-21 | — | — | WO | disclosed |