Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MBOAT4 | Q96T53 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL868326 | 0.84 | KDM4E (0.49) | ALDH1A1KDM4ESMN1; SMN2MAPK1MAPT | |
| SCHEMBL14375957 | 0.83 | KDM4E (0.54) | ALDH1A1KDM4ESMN1; SMN2MAPK1MAPT | |
| SCHEMBL8117996 | 0.82 | KDM4E (0.47) | ALDH1A1KDM4ESMN1; SMN2MAPK1MAPT | |
| SCHEMBL10372114 | 0.82 | NPC1 (0.56) | ALDH1A1KDM4ESMN1; SMN2MAPK1MAPT | |
| SCHEMBL5263898 | 0.79 | KDM4E (0.42) | ALDH1A1KDM4ESMN1; SMN2MAPK1MAPT | |
| SCHEMBL5225381 | 0.78 | KDM4E (0.52) | ALDH1A1KDM4ESMN1; SMN2MAPK1MAPT | |
| SCHEMBL4819849 | 0.76 | MBOAT4 (0.44) | ALDH1A1MBOAT4POLBTSHRKMT2A | |
| SCHEMBL4821793 | 0.76 | TSHR (0.45) | ALDH1A1KDM4ESMN1; SMN2MAPK1MAPT | |
| SCHEMBL22968380 | 0.75 | MBOAT4 (0.71) | MBOAT4 | |
| SCHEMBL5231940 | 0.75 | ENPP1 (0.55) | ALDH1A1KDM4ESMN1; SMN2MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7307172-B2 | 7-amino triazolopyrimidines for controlling harmful fungi | BASF AKTIENGESELLSCHAFT (DE) | 2007-12-11 | — | — | US | claimed |
| EP-1414302-B1 | 7-AMINO TRIAZOLOPYRIMIDINES FOR CONTROLLING HARMFUL FUNGI | BASF AG (DE) | 2007-03-21 | — | — | EP | claimed |