Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MBOAT4 | Q96T53 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5229531 | 0.78 | ALDH1A1 (0.47) | KDM4EALDH1A1POLBHPGDSMN1; SMN2 | |
| SCHEMBL10372114 | 0.78 | NPC1 (0.56) | KDM4EALDH1A1HPGDSMN1; SMN2MBOAT4 | |
| SCHEMBL5228618 | 0.77 | MBOAT4 (0.60) | MBOAT4ENPP1 | |
| SCHEMBL5228518 | 0.74 | MBOAT4 (0.44) | MBOAT4 | |
| SCHEMBL5226718 | 0.72 | MBOAT4 (0.45) | MBOAT4 | |
| SCHEMBL5225556 | 0.69 | MBOAT4 (0.43) | MBOAT4 | |
| SCHEMBL5229255 | 0.69 | MBOAT4 (0.42) | MBOAT4 | |
| SCHEMBL5228809 | 0.69 | MBOAT4 (0.50) | MBOAT4 | |
| SCHEMBL5226752 | 0.68 | MBOAT4 (0.67) | KDM4EALDH1A1HPGDMBOAT4ENPP1 | |
| SCHEMBL5593173 | 0.67 | ALDH1A1 (0.72) | KDM4EALDH1A1POLBSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7307172-B2 | 7-amino triazolopyrimidines for controlling harmful fungi | BASF AKTIENGESELLSCHAFT (DE) | 2007-12-11 | — | — | US | claimed |
| EP-1414302-B1 | 7-AMINO TRIAZOLOPYRIMIDINES FOR CONTROLLING HARMFUL FUNGI | BASF AG (DE) | 2007-03-21 | — | — | EP | claimed |