SCHEMBL5229538

SCHEMBL5229538

COc1ccc(SC(C)=O)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.53
ALDH1A1 P00352 1/20 0.53
HPGD P15428 1/20 0.53
CES2 O00748 2/20 0.50
CES1 P23141 2/20 0.50
MTNR1A P48039 1/20 0.50
MTNR1B P49286 1/20 0.50
HDAC3 O15379 1/20 0.50
HDAC4 P56524 1/20 0.50
HDAC1 Q13547 1/20 0.50
HDAC7 Q8WUI4 1/20 0.50
HDAC2 Q92769 1/20 0.50
HDAC10 Q969S8 1/20 0.50
HDAC11 Q96DB2 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
HDAC9 Q9UKV0 1/20 0.50
HDAC5 Q9UQL6 1/20 0.50
CA1 P00915 6/20 0.48
CA2 P00918 6/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8488030 0.83 HDAC3 (0.45) MAPTALDH1A1HPGDCES2CES1
SCHEMBL14341653 0.83 HPGD (0.46) MAPTALDH1A1HPGDCA1CA2
SCHEMBL11568437 0.81 HPGD (0.51) MAPTALDH1A1HPGDCES2CES1
SCHEMBL7306933 0.81 CA1 (0.55) MAPTALDH1A1HPGDCES2CES1
SCHEMBL28338045 0.79 CA1 (0.50) MAPTALDH1A1HPGDCES2CES1
SCHEMBL29267425 0.79 MAPT (0.46) MAPTALDH1A1HPGDCES2CES1
SCHEMBL14341658 0.79 MAPT (0.47) MAPTALDH1A1HPGDMTNR1AMTNR1B
SCHEMBL22735096 0.78 ALDH1A1 (0.49) MAPTALDH1A1HPGDCES2CES1
SCHEMBL11338721 0.78 ALDH1A1 (0.49) MAPTALDH1A1HPGDCES2CES1
SCHEMBL11768736 0.78 PLK1 (0.53) MAPTALDH1A1HPGDCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109796383-B 1-thiophenyl-N-acetyl-2-naphthylamine and its derivative and synthesis method 湘潭大学 2020-09-18 CN claimed
CN-107229186-B Colored photosensitive resin composition, color filter and display device comprising same 东友精细化工有限公司 2021-06-29 CN disclosed
CN-107168011-B Cyan photosensitive resin composition, cyan color filter comprising same, and display device 东友精细化工有限公司 2021-04-13 CN disclosed
CN-106918992-B Green photosensitive resin composition, color filter comprising same, and display device 东友精细化工有限公司 2021-04-06 CN disclosed
CN-109796383-B 1-thiophenyl-N-acetyl-2-naphthylamine and its derivative and synthesis method 湘潭大学 2020-09-18 CN disclosed
CN-105319837-B Photoresist pattern forming method 东友精细化工有限公司 2019-10-25 CN disclosed
CN-110361933-A Light converts resin combination, light conversion layer folds substrate and image display device 东友精细化工有限公司 2019-10-22 CN disclosed
CN-105319850-B Photosensitive polymer combination 东友精细化工有限公司 2019-10-11 CN disclosed
CN-110300791-A Quantum dot dispersion, self-luminous photosensitive resin composition, color filter, and image display device 东友精细化工有限公司 2019-10-01 CN disclosed
CN-110275392-A Light converts resin combination, light conversion layer folds substrate and image display device 东友精细化工有限公司 2019-09-24 CN disclosed
CN-101121825-A Resin composition capable of polymerizing SUMITOMO CHEMICAL CO (JP) 2008-02-13 CN disclosed
EP-1373233-B1 DERIVATIVES OF N-(ARYLSULFONYL)BETA-AMINOACIDS COMPRISING A SUBSTITUTED AMINOMETHYL GROUP, THE PREPARATION METHOD THEREOF AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING SAME SANOFI AVENTIS (FR) 2007-09-05 EP disclosed
CN-1940720-A Photosensitive resin composition SUMITOMO CHEMICAL CO (JP) 2007-04-04 CN disclosed
CN-1904732-A Photosensitive resin composition for photosensitive clearance material SUMITOMO CHEMICAL CO (JP) 2007-01-31 CN disclosed
CN-1821873-A Photosensitive resin compound SUMITOMO CHEMICAL CO (JP) 2006-08-23 CN disclosed
CN-1707358-A Photosensitive resin composition SUMITOMO CHEMICAL CO (JP) 2005-12-14 CN disclosed
CN-1654990-A Pigment dispersion inhibitor SUMITOMO CHEM CORP (JP) 2005-08-17 CN disclosed
EP-1373233-A1 DERIVATIVES OF N-(ARYLSULFONYL)BETA-AMINOACIDS COMPRISING A SUBSTITUTED AMINOMETHYL GROUP, THE PREPARATION METHOD THEREOF AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING SAME Sanofi-Aventis (FR) 2004-01-02 EP disclosed
WO-2002076964-A1 DERIVATIVES OF N-(ARYLSULFONYL)BETA-AMINOACIDS COMPRISING A SUBSTITUTED AMINOMETHYL GROUP, THE PREPARATION METHOD THEREOF AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING SAME SANOFI-SYNTHELABO (FR) 2002-10-03 WO disclosed
EP-0742201-A1 PROCESS FOR PRODUCING AROMATIC OR HETEROAROMATIC SULFUR COMPOUNDS SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1996-11-13 EP disclosed