SCHEMBL522986

SCHEMBL522986

CC=CC1C(C(=O)OC)C1(C)C

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
ALDH1A1 P00352 1/20 0.32
CYP1A2 P05177 1/20 0.31
TSHR P16473 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2166744 1.00 LMNA (0.41) LMNAALDH1A1CYP1A2TSHRCYP2C19
SCHEMBL29246847 1.00 LMNA (0.41) LMNAALDH1A1CYP1A2TSHRCYP2C19
SCHEMBL6438837 1.00 LMNA (0.41) LMNAALDH1A1CYP1A2TSHRCYP2C19
SCHEMBL2167379 1.00 LMNA (0.41) LMNAALDH1A1CYP1A2TSHRCYP2C19
SCHEMBL2167375 1.00 LMNA (0.41) LMNAALDH1A1CYP1A2TSHRCYP2C19
SCHEMBL6438832 1.00 LMNA (0.41) LMNAALDH1A1CYP1A2TSHRCYP2C19
SCHEMBL7641481 1.00 LMNA (0.41) LMNAALDH1A1CYP1A2TSHRCYP2C19
SCHEMBL7643956 1.00 LMNA (0.41) LMNAALDH1A1CYP1A2TSHRCYP2C19
SCHEMBL522985 1.00 LMNA (0.41) LMNAALDH1A1CYP1A2TSHRCYP2C19
SCHEMBL10415142 0.82 LMNA (0.43) LMNAALDH1A1CYP1A2TSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118063315-A Method for preparing Z-meta-chrysanthemate 江苏扬农化工股份有限公司 2024-05-24 CN disclosed
CN-103958533-B Optically active bisoxazoline compound, asymmetric catalyst, and method for producing optically active cyclopropane compound using same SUMITOMO CHEMICAL CO.,LTD. (JP) 2016-02-10 CN disclosed
EP-1783111-B1 METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANECARBOXYLATE COMPOUND SUMITOMO CHEMICAL CO (JP) 2015-04-08 EP disclosed
CN-102365255-B Method for producing alcohol compound and catalyst therefor SUMITOMO CHEMICAL CO 2015-01-07 CN disclosed
CN-102365254-B Method for producing alcohol compound SUMITOMO CHEMICAL CO 2014-08-27 CN disclosed
CN-103958533-A Optically active bis-oxazoline compound, asymmetric catalyst, and method for producing optically active cyclopropane compound using same SUMITOMO CHEMICAL CO 2014-07-30 CN disclosed
CN-101326150-B Method for producing olefin compound SUMITOMO CO LTD 2013-05-01 CN disclosed
EP-1681282-B1 METHOD FOR PRODUCING 3,3-DIMETHYL-2-(1-PROPENYL) CYCLOPROPANE CARBOXYLATE SUMITOMO CHEMICAL CO (JP) 2013-01-23 EP disclosed
EP-1970368-B1 METHOD FOR PRODUCING OLEFIN COMPOUND SUMITOMO CHEMICAL CO (JP) 2012-08-29 EP disclosed
CN-1852887-B Process for producing optically active cyclopropane compound and asymmetric copper complex for use in the same SUMITOMO CO LTD 2012-08-15 CN disclosed
EP-1203760-A1 Method for producing cyclopropanecarboxylates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-05-08 EP disclosed
US-20020052525-A1 Method for producing cyclopropanecarboxylates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-05-02 US disclosed
EP-1188735-A1 Process for producing carbonyl or hydroxy compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-03-20 EP disclosed
US-20020025906-A1 Process for producing carbonyl or hydroxy compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-02-28 US disclosed
US-20010014755-A1 Method for producing 2,2-dimethyl-3-(1-propenyl)cyclopropanecarboxylate ester COMVERGE, INC. 2001-08-16 US disclosed
US-6207429-B1 REACTING 2,2-DIMETHYL-3-(SUBSTITUTED VINYL)CYCLOPROPANE-1-CARBOXYLIC ACID C1-C4 ESTERS WITH STEREOSPECIFIC ESTERASE FROM ARTHROBACTER TO FORM TRANS-2,2-DIMETHYL-3-(SUBSTITUTED VINYL)CYCLOPROPANE-1-CARBOXYLIC ACID SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-03-27 US disclosed
EP-1061065-A2 Methods for producing cyclopropane carboxylates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-12-20 EP disclosed
CN-1255489-A Method for preparing cyclopropane carboxylic ester SUMITOMO CHEM ENG (JP) 2000-06-07 CN disclosed
EP-0992479-A1 Method for producing cyclopropanecarboxylates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-04-12 EP disclosed
EP-0959139-A1 Method for producing optically active cyclopropanecarboxylic acid SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-11-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020052525-A1 Method for producing cyclopropanecarboxylates CYP8B1, SRD5A2, CYP21A2 LMNA 1815/4885ALDH1A1 671/4885CYP1A2 39/4885
US-20010014755-A1 Method for producing 2,2-dimethyl-3-(1-propenyl)cyclopropanecarboxylate ester DHCR24, CYP2E1, PPT1 LMNA 3185/4885ALDH1A1 64/4885CYP1A2 108/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.