Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.59 |
| ▸ | RAB9A | P51151 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.54 |
| ▸ | PPARG | P37231 | 3/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5223950 | 0.84 | NR1H4 (0.71) | NPC1RAB9ANR1H4PPARGPPARA | |
| SCHEMBL1687867 | 0.82 | NPC1 (0.79) | NPC1RAB9AMAPTCA1CA2 | |
| SCHEMBL5223315 | 0.82 | RAB9A (0.73) | NPC1RAB9AALDH1A1GLAATM | |
| SCHEMBL7291713 | 0.82 | NPC1 (0.79) | NPC1RAB9AMAPTCA1CA2 | |
| SCHEMBL7293746 | 0.82 | NPC1 (0.79) | NPC1RAB9AMAPTCA1CA2 | |
| SCHEMBL12636930 | 0.80 | NPC1 (0.61) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL13744870 | 0.80 | CA2 (0.58) | NPC1RAB9AMAPTRECQLCA1 | |
| SCHEMBL7295495 | 0.79 | POLB (0.72) | NPC1RAB9AALDH1A1GLAATM | |
| SCHEMBL28199719 | 0.79 | KCNK9 (0.58) | NPC1RAB9AALDH1A1GLAATM | |
| SCHEMBL17546531 | 0.78 | AKR1C3 (0.45) | NPC1RAB9AALDH1A1GLAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1014962-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2007-06-27 | — | — | EP | disclosed |
| EP-1014962-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999000121-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | disclosed |