Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 8/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.39 |
| ▸ | HTR2C | P28335 | 5/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | MAT2A | P31153 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5231827 | 0.99 | HTR2A (0.40) | HTR2AKCNH2HTR2CDRD2MAT2A | |
| SCHEMBL5238399 | 0.90 | SLC6A3 (0.37) | SLC6A3 | |
| SCHEMBL2995670 | 0.83 | HTR2A (0.42) | HTR2AKCNH2HTR2CDRD2MAT2A | |
| SCHEMBL2987900 | 0.83 | HTR2A (0.39) | HTR2AKCNH2HTR2CDRD2MAT2A | |
| SCHEMBL2995376 | 0.82 | HTR2A (0.43) | HTR2AKCNH2HTR2CDRD2MAT2A | |
| SCHEMBL2995078 | 0.82 | HTR2A (0.39) | HTR2AKCNH2HTR2CDRD2SLC6A3 | |
| SCHEMBL5231212 | 0.82 | HTR2A (0.39) | HTR2AKCNH2HTR2CDRD2MAT2A | |
| SCHEMBL5233174 | 0.74 | CYP1A2 (0.34) | HTR2AKCNH2HTR2CDRD2MAT2A | |
| SCHEMBL13211532 | 0.74 | PTGS1 (0.46) | HTR2AKCNH2HTR2CDRD2 | |
| SCHEMBL2997440 | 0.74 | GCGR (0.40) | HTR2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664059-B1 | THIENOPYRROLES AS ANTIVIRAL AGENTS | ANGELETTI P IST RICHERCHE BIO (IT) | 2007-09-12 | — | — | EP | claimed |