Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.32 |
| ▸ | MAT2A | P31153 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2990104 | 0.86 | CYP1A2 (0.35) | CYP1A2CYP2D6CYP2C9HPGDCYP2C19 | |
| SCHEMBL13211561 | 0.77 | FNTA (0.34) | KDM4EFNTAFNTBDRD2HTR2A | |
| SCHEMBL5230100 | 0.74 | HTR2A (0.39) | MAT2ASLC6A3DRD2HTR2AHTR2C | |
| SCHEMBL13475953 | 0.73 | MAPT (0.43) | CYP2C9HPGDCYP2C19KDM4ENPSR1 | |
| SCHEMBL5231827 | 0.73 | HTR2A (0.40) | MAT2ASLC6A3DRD2HTR2AHTR2C | |
| SCHEMBL13211556 | 0.71 | RAB9A (0.37) | HPGDDRD2HTR2AHTR2CKCNH2 | |
| SCHEMBL5229977 | 0.70 | CNR1 (0.36) | CYP2C19SLC6A9 | |
| SCHEMBL5231212 | 0.70 | HTR2A (0.39) | MAT2ADRD2HTR2AHTR2CKCNH2 | |
| SCHEMBL13211559 | 0.69 | TACR2 (0.39) | HPGDKDM4EDRD2HTR2AHTR2C | |
| SCHEMBL13211558 | 0.68 | MAT2A (0.33) | MAT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664059-B1 | THIENOPYRROLES AS ANTIVIRAL AGENTS | ANGELETTI P IST RICHERCHE BIO (IT) | 2007-09-12 | — | — | EP | claimed |